نتایج جستجو برای: prognostic scoring
تعداد نتایج: 147930 فیلتر نتایج به سال:
Since introduction of oral chemotherapy in the treatment of CML there is a continual effort for estimation of prognosis including future response to the therapy. Despite the first efficient prognostic scoring systems were designed for the patients treated with busulfan or hydroxyurea and interferon-alpha, respectively, Sokal and Hasford (Euro) scores are used for the patients treated with tyros...
AIMS Evaluating expression of the human epidermal growth factor receptor 2 (HER2) by visual examination of immunohistochemistry (IHC) on invasive breast cancer (BCa) is a key part of the diagnostic assessment of BCa due to its recognized importance as a predictive and prognostic marker in clinical practice. However, visual scoring of HER2 is subjective, and consequently prone to interobserver v...
Acute myeloid leukemia and myelodysplastic syndrome with inv(3)(q21q26.2)/t(3;3)(q21;q26.2) have a poor prognosis. Indeed, the inv(3)(q21q26.2)/t(3;3)(q21;q26.2) has been recognized as a poor risk karyotype in the revised International Prognostic Scoring System. However, inv(3)(q21q26.2)/t(3;3)(q21;q26.2) is not among the cytogenetic abnormalities pathognomonic for diagnosis of acute myeloid le...
Primary myelofibrosis (PMF) is a rare chronic BCR-ABL1-negative myeloproliferative neoplasm characterized by progressive bone marrow fibrosis, inefficient hematopoiesis, and shortened survival. The clinical manifestations of PMF include splenomegaly, consequent to extramedullary hematopoiesis, pancytopenias, and an array of potentially debilitating constitutional symptoms. The diagnosis is base...
Pneumonia Severity Index and CURB 65 are the two most important prognostic scoring tools to predict mortality for patients with CAP. These tools accurately predict mortality but do not directly measure disease severity. The clinical assessment is still required to decide hospital admission or ICU care. Prognostic scoring systems have been used to assist in the site-of-care decisions, with limit...
Diffuse and focal bone marrow infiltration patterns detected by magnetic resonance imaging have been shown to be of prognostic significance in all stages of monoclonal plasma cell disorders and have, therefore, been incorporated into the definition of the disease. The aim of this retrospective analysis was to develop a rapidly evaluable prognostic scoring system, incorporating the most signific...
Identification of reliable predictive biomarkers and new therapeutic targets is a critical step for significant improvement in patient outcomes. Here, we developed a multi-step bioinformatics analytic strategy to mine large omics and clinical data to build a prognostic scoring system for predicting the overall survival (OS) of lung adenocarcinoma (LuADC) patients. In latter we first identified ...
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