نتایج جستجو برای: programmed death

تعداد نتایج: 287506  

Journal: :Plant Biotechnology 1999

Journal: :Journal of Biological Chemistry 2004

Journal: :gastroenterology and hepatology from bed to bench 0
emilie hangen guido kroemer nazanine modjtahedi

in many models of programmed cell death, the mitochondrial protein aif translocates to the nucleus, where it induces the chromatin condensation and dna degradation. however, today it is well established that this flavoprotein is bifunctional. in addition to its lethal function in the nucleus of dying cells, aif plays a vital bioenergetic role in healthy ones by regulating mainly the activity of...

Journal: :Trends in plant science 2000
A Jones

Research on programmed cell death in plants is providing insight into the primordial mechanism of programmed cell death in all eukaryotes. Much of the attention in studies on animal programmed cell death has focused on determining the importance of signal proteases termed caspases. However, it has recently been shown that cell death can still occur even when the caspase cascade is blocked, reve...

2018
Kousaku Mimura Jun Liang Teh Hirokazu Okayama Kensuke Shiraishi Ley-Fang Kua Vivien Koh Duane T Smoot Hassan Ashktorab Takahiro Oike Yoshiyuki Suzuki Zul Fazreen Bernadette R Asuncion Asim Shabbir Wei-Peng Yong Jimmy So Richie Soong Koji Kono

Despite multidisciplinary treatment for patients with advanced gastric cancer, their prognosis remains poor. Therefore, the development of novel therapeutic strategies is urgently needed, and immunotherapy utilizing anti-programmed death 1/-programmed death ligand-1 mAb is an attractive approach. However, as there is limited information on how programmed death ligand-1 is upregulated on tumor c...

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