www.sciencemag.org SCIENCE VOL 337 6 JULY 2012 5 COVER Structure of the Wnt signaling molecule (red) in complex with the Frizzled ligand-binding domain (yellow), schematically depicted as connected to the cell surface. A key feature of this structure is the visualization of a lipid group (blue) on Wnt directly engaging Frizzled. The Wnt/Frizzled mode of binding paves the way for the design of W...

This Theme Section consists of 11 essays aiming to explore diverse issues related to academic freedom and tenure, presenting the views and thoughts of 15 scholars from different disciplines. Historical, legal, theoretical, philosophical, political and educational aspects of academic freedom and tenure are addressed; the decline in productivity of tenured faculty is questioned; and the effect of...

In this interconnected age, interpretations of academic freedom have been legally contentious for virtual environments being established in such forums as the World Wide Web and electronic mail on the Internet. This paper addresses the legal issues that arise from the conflict between the concept of academic freedom in higher education and its scope and application in cyberspace. Challenges to ...

Research thrives – indeed can hardly do without – data. It is the raw information upon which better understanding, and better knowledge is based. Indeed one whole assumption underpinning some visions of Electronic Government – such as Wiki-Gov – is the idea that data which has been collected for a specific government task can be re-used in ways which further public service goals through citizen...