In Ayurveda, Withania somnifera is commonly known as Ashwagandha, its roots are specifically used in medicinal and clinical applications. It possesses numerous therapeutic actions which include anti-inflammatory, sedative, hypnotic and narcotic. Extracts from this plant have been reported for its anticancer properties. In this study we evaluated for the first time, the cytotoxic effect of Witha...

The present study deals with the diversity and distribution of VAMF at different sites with different selected plants. Maximum number of VAMF species were found at site IV (57 species) out of which Glomus species was most dominant (58%), followed by Acaulospora (19%), Scutellospora (8%), Sclerocystis (4.8%) and Gigaspora (1.6%) respectively. In site II 56 species of VAMF were observed with Glom...

Withania somnifera (L.) Dunal (Indian ginseng, winter cherry, Solanaceae) is widely used in traditional medicine. Roots are either chewed or used to prepare beverages (aqueous decocts). The major secondary metabolites of Withania somnifera are the withanolides, which are C-28-steroidal lactone triterpenoids. Withania somnifera extracts exert chemopreventive and anticancer activities in vitro an...

BACKGROUND Glycowithanolides (Withaferin A), is one of the main withanolides active principle isolated from plant Withania somnifera and is claimed that it possess the aphrodisiac, sedative, rejuvenate and life prolonging properties. OBJECTIVE In the present investigation, antioxidant activity of active principles of Withania somnifera was tested against D-galactose induced oxidative stress i...

objective: the main objective of the current study was to observe the ameliorative effect of withania somnifera on arsenic-induced testicular toxicity by exploring the crucial parameters such as sperm counts, sperm motility, hormonal assay and lipid peroxidation including histopathology. materials and methods: in the present study, arsenic in the form of sodium arsenite was administered orally ...

Withania somnifera extracts are known for their anti-cancerous, anti-inflammatory and antioxidative properties. One of their mechanisms of actions is to modulate mitochondrial function through increasing oxidative stress. Recently 'priming' has been suggested as a potential mechanism for enhancing cancer cell death. In this study we demonstrate that 'priming', in HT-29 colon cells, with W. somn...

The present study was to compare the Phytochemical and Antimicrobial analysis of W. somnifera and W. obtusifolia. In the Ethanolic leaf and root extract of Withania species were screened for phytochemical compounds by qualitative and FT-IR, UV method. Withania species have been used for remedies of human pathogen because they contain therapeutic compounds. This research work was mainly focused ...

In this study, a novel technique for biosynthesizing of gold nanoparticles (GNPs) using Withania somnifera as reductants and stabilizers is reported. Biosynthesis of anisotropic gold nanoparticles using ethanolic extract of Withania somnifera leaf and their potential as IR blockers has been demonstrated. The phenolic groups (–OH) residue was identified as the active functional group for gold io...

Withania somnifera, commonly known as Ashwagandha, is an important medicinal plant that has been used in Ayurvedic and indigenous medicine for over 3,000 years. In view of its varied therapeutic potential, it has also been the subject of considerable modern scientific attention. The major chemical constituents of the Withania genus, the withanolides, are a group of naturally occurring C28-stero...

The yield parameters and cost economics of Withania somnifera were studied using Integrated Nutrient Management (INM) treatments. Withania somnifera is cultivated in around 10,780 ha with a production of 8429 tones in India. The annual demand of this herb increased from 7028 tones (2001-2002) to 9127 tones (2004-2005). The field experiment was conducted at the research farm of Department of Pla...