Ursolic acid (UA) is a major bioactive component in many traditional medicinal plants including pomegranate (Punica granatum L.) flower. In vitro and in vivo studies have both revealed that UA has  many  important  biological  functions.In  this  study,  a  rapid  and  efficient  procedure  for preparation of UA from an Iranian pomegranate flower cultivar using ultrasound-assisted extraction fo...

Eight major chemicals are identified after analyzing the essential oil of the seeds of three medicinal plants Punica granatum, Vitis vinifera and Cucurbita maxima, using Gas Chromatography/Mass Spectrometry (GC-MS). Only three of the identified chemicals (Farnesene, Docosane and Tetracosane) were found in all three samples, but in varying proportions. Trans-Squalene was found in Cucurbita maxim...

2. Pomegranate (Punica granatum) allergy: clinical and immunological findings. Ann Allergy Asthma Immunol. 2009;103:178--80. 3. Enrique E, Utz E, Utaz M, Mateo JA, Castello JV, Malek T, et al. Allergy to lipid transfer proteins: cross-reactivity among pomegranate, hazelnut, and peanut. Ann Allergy Asthma Immunol. 2006;96:122--3. 4. Gangeni S, Mistrello G, Roncarolo D, Amato S, Minciullo PL. Pom...

Arils from six pomegranate (Punica granatum L.) varieties grown in the Mediterranean region of Turkey were tested for their antimicrobial properties by the agar diffusion and minimum inhibitory concentration (MIC) methods against seven bacteria: (Bacillus megaterium DSM 32, Pseudomonas aeruginosa DSM 9027, Staphylococcus aureus Cowan 1, Corynebacterium xerosis UC 9165, Escherichia coli DM, Ente...

Acute subcutaneous administration of angiotensin-II (Ang II-150μg/kg) causes a rise in blood pressure in normal Wistar rats. Administration of Punica granatum juice extract (PJ100 mg/kg and 300 mg/kg; p.o.) for 4 weeks in angiotensin-II treated rats significantly (P<0.05) reduced the mean arterial blood pressure and vascular reactivity changes to various catecholamines. PJ treatment significant...

Aims: In our previous studies, we showed the inhibitory effects of Punica granatum L. flower and Rhus coriaria L. fruit water extracts on dental plaque accumulation by several bacteria, especially Streptococcus mutans (S. mutans), on orthodontic wire by in vitro assays. In this study, the anti-cariogenic properties of the extracts were evaluated by assessing their effects on expression of glyco...

      Punica granatum is used as a medicinal plant, and its fruit concentrate has been used for the prevention and treatment of liver diseases in Iran. The effects of different concentrations of the hydroalcoholic, ethyl acetate and n-hexane extracts of the Punica granatum (fruit juice and seed) were investigated against CCl4- induced cytotoxicity in HepG2...

More than 80% of the worldís population depend upon traditional medicines for various skin diseases (1). Recently, the traditional use of plants for wound healing has received attention by the scientific community (1, 2). Approximately one-third of all traditional medicines in use are for the treatment of wounds and skin disorders, compared to only 1-3 % of modern drugs (3). Wound healing is a ...

Pomegranate, Punica granatum L. (Punicaceae), as a medicinal and nutritional ancient fruit, has an outstanding medical history throughout the world. Each of compartments of pomegranate has interesting pharmacological activity. Juice, leaf, flower, and peels of pomegranate possess potent antioxidant properties, while juice, peel and oil are all weakly estrogenic activity. Pomegranate seeds have ...

The mechanistic pathway for the antidiabetic efficacy of ethanolic extract of Punica granatum flowers (PgEFet) has been investigated by measuring the status of blood glucose, plasma insulin, carbohydrate metabolizing enzymes, lipid peroxidation and antioxidants as biochemical end points in streptozotocin induced diabetic rats. Diabetes mellitus was induced by single intraperitoneal injection of...