BACKGROUND Putrescine oxidase (EC 1.4.3.10) is of interest for the microbial production unsubstituted platform nitrogen (N-)heterocycles, because it only requires inexpensive oxygen as co-substrate. from Rhodococcus erythropolis (Re-PuO) was shown previously to catalyze oxidation cadaverine; however, there little information in literature about robustness this enzyme biotechnological applicatio...

Giant cell arteritis(GCA) is a primary granulomatous vasculitis affecting the large and medium sized arteries. We present here a case of GCA with pyrexia of unknown origin (PUO) as the presenting manifestation in the absence of other typical features. On evaluation, the patient had raised inflammatory markers with features of large vessel vasculitis on whole body PET-CT scan. The colour doppler...

We report a case of EDTA induced pseudothrombocytopenia (EDTA-PTCP) in a patient with scrub typhus who was referred as a case of pyrexia of unknown origin (PUO) with marked thrombocytopenia and treated with platelet transfusion. Blood smear examination revealed numerous platelet aggregates. CBC analysis using citrate and lithium-heparin as anticoagulants as well as a peculiar WBC histogram aide...

Supravalvular aortic stenosis is a less common form of left ventricular outflow tract obstruction (LVOTO); commonest being the valvular aortic stenosis followed by valvular and subvalvular forms respectively. Most of the supravalvular aortic stenosis is associated with Williams syndrome; isolated supravalvular aortic stenosis is further rarer. We present a case of isolated SVAS with infective e...

Case report A 63 year old lady presented to a peripheral centre polyarthralgia, multiple tender and erythematous nodules over her face, elbows, back and legs and continuous fever of 2 months duration. Routine investigations being negative, she was referred for further evaluation of PUO. On presentation, the patient was febrile. Apart from the nodules, examination revealed bilaterally thickened ...

Objective To find out the incidence of Mycoplasma pneumoniae infection in patients with pyrexia of unknown origin. Design Prospective study. Setting University Paediatric Unit, Teaching Hospital, Karapitiya. Method Patients presenting with fever of more than 7 days with no obvious reason for its occurrence (PUO) to University Paediatric Unit, Teaching Hospital, Karapitiya from January to Novemb...

RIASSUNTO. Il teorema di Ramsey [6] per coppie e’ provabile classicamente ma non intuizionisticamente [2]. In questa nota mostriamo che Ramsey si puo’ rienunciare in una forma intuizionisticamente provabile, informativa (o quanto meno priva di negazioni), e classicamente equivalente all’originale. A differenza di precedenti tentativi, non utilizziamo ne’ il noncontroesempio come in [1], [5], ne...

Hepatosplenic tuberculosis (HST), rarely encountered in surgical practice, is seen in-patients with disseminated tuberculosis. A 20-year-old female presenting with pyrexia of unknown origin (PUO) was subsequently diagnosed to have lymph-nodal tuberculosis with involvement of liver and spleen. Despite anti-tuberculosis treatment (ATT) for 3 months, clinical improvement did not occur and fever pe...

Background: Rickettsial diseases are among the most obscured re-emerging arthropod borne zoonotic infections that are being increasingly recognized as one of the causes of pyrexia of unknown origin (PUO). Presenting with varied and non-specific symptoms, ignorance and low index of suspicion, they are often under diagnosed due to the unavailability of the reliable diagnostic test. Appropriate di...