OBJECTIVE To determine whether diabetes and sex were factors associated with ambulatory function, endothelial cell inflammation, oxidative stress, and apoptosis, and with circulating biomarkers of inflammation and antioxidant capacity in patients with peripheral artery disease (PAD) and claudication. MATERIALS/METHODS Ambulatory function of 180 symptomatic men and women with PAD was assessed ...

Silvopastoral system (SPS) has been considered as a sustainable management contribute to greenhouse gas (GHG) reduction, among other benefits compared with open pasture. However, little research conducted on the soil and tree biomass carbon stored in traditional pasture dispersed trees (PWT) monoculture (PM). The present study was Ecuadorian Amazon Region (EAR), along an elevational gradient fr...

BACKGROUND This prospective, randomized, controlled clinical trial compared changes in primary outcome measures of claudication onset time (COT) and peak walking time (PWT), and secondary outcomes of submaximal exercise performance, daily ambulatory activity, vascular function, inflammation, and calf muscle hemoglobin oxygen saturation (StO2) in patients with symptomatic peripheral artery disea...

The aim of this study was to investigate the analgesic mechanism of electroacupuncture (EA) in the treatment of neuropathological pain. A total of 60 Sprague-Dawley rats were randomly divided into three groups, namely the spinal nerve ligation (SNL), electroacupuncture (SNL + EA) and normal control groups, with 20 rats in each group. The up-down method was used to determine the bipedal 50% mech...

OBJECTIVE This article reports the early results of a novel sling used for the treatment of female stress urinary incontinence (SUI). This sling has a piece of autologous rectus fascia in its middle part and two arms of polypropylene mesh. MATERIAL AND METHODS The study included 44 women with SUI. The preoperative work-up involved complete history taking, physical examination, cough stress te...

Assignment: One approach to solving the measurement problem in quantum theory proposes that a certain quantity Q is `preferred' in that a quantum system always has a de nite value for it. So Q needs to be chosen so that: 1. its de nite values appropriately explain the de niteness of the macrorealm, and this will presumably involve equations of motion for the values that mesh suitably with the q...

Paclitaxel-induced peripheral neuropathy is not completely known. Since the sodium channel Nav1.7 has been implicated in pain perception, and is upregulated in pain disorders, we investigated the effect of paclitaxel on Nav1.7 expression in rat dorsal root ganglion (DRG) neurons. Thirty Sprague-Dawley rats were administered either 2 mg/kg paclitaxel or vehicle on days 0, 2, 4 and 6. To evaluate...

BACKGROUND Nerve injury-induced neuropathic pain is a major health problem worldwide. Notch signaling is a highly conserved pathway in evolution, which has an important role in synaptic plasticity and inflammation in central nervous system. The present study was designed to investigate the potential role of notch signaling in the development of neuropathic pain. METHODS The neuropathic pain w...

PURPOSE We assessed the risk of radiation pneumonitis (RP) in terms of dosimetric parameters in breast cancer patients, who received radiotherapy using the partially wide tangent technique (PWT), following breast conservation surgery (BCS). METHODS We analyzed the data from 100 breast cancer patients who underwent radiotherapy using PWT. The entire breast, supraclavicular lymph node, and inte...