BACKGROUND Drug-induced increase in QT dispersion has been associated with potentially fatal ventricular arrhythmias. Little is known about the use of psychotropic substances, alone or in combination with other drugs on QT dispersion. OBJECTIVES To evaluate the impact of psychotropic drugs on QT interval dispersion in adults. METHODS An observational cohort study was designed involving 161 ...

The link between increased QT dispersion and cardiac death in subjects with diabetes and arterial disease is well recognised. Corrected QT dispersion was studied in subjects with end stage renal failure on haemodialysis. Thirty one stable, chronic subjects on haemodialysis had 12-lead electrocardiograms (ECGs) taken before and after a single haemodialysis session. The QT interval was measured m...

Introduction Determination of the QT interval dispersion by means of a standard ECG at rest has been widely used for cardiovascular risk assessment during the last 15 years as one of the recent explanations for the development of life threatening ventricular arrhythmias. However, little is known about the relation between QT dispersion and the severity of coronary artery atherosclerosis as defi...

OBJECTIVE To investigate whether QT dispersion is a reliable index of the severity of aortic stenosis and left ventricular hypertrophy in the setting of aortic stenosis. DESIGN A retrospective analysis of the results of echocardiography and electrocardiography before and after aortic valve replacement. SETTING Tertiary centre. PATIENTS 36 men (30 white and six black) with symptomatic aort...

Background: QT dispersion (QTd) especially after ischemic heart disease and myocardial infarction is a prognostic predictor of mortality, in adult medicine.  Objective: This study was undertaken to determine the correlation between QT dispersion and neonatal stress. Neonates were divided into 3 groups: normal term (30 cases), normal preterm (30 cases) and sick neonates (36 cases), born between ...

OBJECTIVE To define the effects of beta(2) adrenergic receptor stimulation on ventricular repolarisation in vivo. DESIGN Prospective study. SETTING Tertiary referral centre. PATIENTS 85 patients with coronary artery disease and 22 normal controls. INTERVENTIONS Intravenous and intracoronary salbutamol (a beta(2) adrenergic receptor selective agonist; 10-30 microg/min and 1-10 microg/min...

INTRODUCTION EKG remains a highly valuable tool for heart disease management. Corrected QT interval dispersion is a useful EKG parameter to assess prognosis in ischemic heart disease and specifically acute coronary syndrome. Understanding QT interval physiopathology helps assess importance of QT measurement in this context. Although increased QT dispersion is an ominous prognostic marker, its u...

Introduction: QT interval represents duration of ventricular electrical systole, i.e., the time required for completion of both ventricular depolarization and repolarization. QT interval duration normally varies between leads on the electrocardiography due to variation of repolarization and re-excitability of different ventricular regions. QT dispersion, defined as the difference between maximu...

The effects of spironolactone or metoprolol added to a conventional treatment protocol on QT dispersion, which is accepted as a sudden cardiac death predictor, were evaluated in heart failure patients.? A total of 105 New York Heart Association class III patients were included in this study. The conventional treatment protocol was standardized by giving ramipril, furosemide, and digoxin to all ...

BACKGROUND Hypertension is an important risk factor for sudden cardiac death, of which the incidence increases with increases in blood pressure. Prolonged QT dispersion has been identified to indicate increased risk of life-threatening ventricular arrhythmia and sudden cardiac death. In this study, QT dispersion was investigated in hypertensive patients during the strain phase of the Valsalva m...