The past decade has seen a wealth of 3D structural information about complex structured RNAs and identification of functional intermediates. Nevertheless, developing a complete and predictive understanding of the folding and function of these RNAs in biology will require connection of individual rate and equilibrium constants to structural changes that occur in individual folding steps and furt...

The 1D quantum confinement of photogenerated excitons in single-walled carbon nanotubes (SWNT) can amplify the detection of molecular adsorption to where single-molecule discrimination is realizable, even from within living cells and tissues. Toward this aim, we present a type 1 collagen film, similar to those used as 3D cell scaffolds for tissue engineering, containing embedded SWNT capable of...

An experimental and theoretical investigation on the chemical reactivity of fullerene cations (Cn+, n = [36, 60]) with amino acid molecules (e.g., isoleucine, C6H13NO2) is performed. The results show that, in gas phase, can react to form fullerene/amino cluster high efficiency. formation rate constants for ion–molecule collision reactions between isoleucine are estimated under pseudo-first-orde...

The simple hydrodynamic description of bimolecular collision rate constants afforded by the Stokes-EinsteinSmoluchowski (SES) equation is tested in a bulk liquid as well as in sodium dodecyl sulfate micelles. Fluorescence quenching of pyrene by three different quenchers is used as a model to study collision rate constants. One quencher is itself a cationic surfactant, one an uncharged long alky...

Molecular recognition is central to biological processes, function, and specificity. Proteins associate with ligands with a wide range of association rate constants, with maximal values matching the theoretical limit set by the rate of diffusional collision. As less is known about RNA association, we compiled association rate constants for all RNA/ligand complexes that we could find in the lite...

We describe in this article the development of a new method for the determination of rate constants of reaction of the hydroxyl radical, generated by radiolysis of water, with almost any possible molecule. It has been designed to provide a fast and reliable screening of antioxidant banks using microplates. Our particular approach is based on the use of the coumarin molecule as a competitor agai...

preliminary investigation on antioxidative potentials of defatted fermented locust bean extract in comparison to defatted non-fermented locust bean was conducted. qualitative antioxidative assessment on the extract was accomplished by screening the phytochemical endowment, and similar bioactive components. also some antioxidative indices were quantitatively evaluated. results showed that the de...

We present accurate state-to-state quantum wave packet calculations of integral cross sections and rate constants for the title reaction. Calculations are carried out on the best available ground 1(2)A' global adiabatic potential energy surface of Deskevich et al. [J. Chem. Phys. 124, 224303 (2006)]. Converged state-to-state reaction cross sections have been calculated for collision energies up...