Spine stereotactic radiosurgery (SSRS) is proving to be one of the most significant advances in the treatment of both metastatic and primary spine tumors. High-dose hypofractionated and single fraction radiation appear to convey better local tumor control than conventional radiation for tumors considered radioresistant, such as renal cell carcinoma and melanoma. Multiple series have demonstrate...

BACKGROUND Ataxic myelopathy due to copper deficiency has been described in ruminant animals and is called swayback. Neurological manifestations due to inherited copper deficiency secondary to the failure of intestinal copper absorption is well recognized as Menkes disease. The neurological consequences of acquired copper deficiency in humans are not well described. OBJECTIVE To report 2 case...

BACKGROUND In primary care, it is often difficult to diagnose cervical myelopathy. However, a delay in treatment could cause irreversible aftereffects. With a brief and effective self-administered questionnaire for cervical myelopathy, cervical myelopathy may be screened more easily and oversight may be avoided. As there is presently no screening tool for cervical myelopathy, the aim of this st...

Adverse effects of IT chemotherapy include arachnoiditis, lumbosacral radiculopathy, leukoencephalopathy, and myelopathy.[3] MRI findings include T2 hyperintensities in the central and posterior columns, cord swelling, or lateral column contrast enhancement. Vacuolar degeneration of the white matter is usually described in MTX myelopathy. Rarely extensive necrotic myelopathy has been noted.[4] ...

we evaluated the specific pattern of pre- and postoperative neurological signs and symptoms of cervical spondylotic myelopathy (csm) to determine [mdings which had a predictive value for surgical outcome. consecutive patients with csm caused by osteophytic ridge or intervertebral disc herniation who underwent anterior cervical decompression and fusion in loghman hakim hospital from 1999-2003 we...

BACKGROUND The present work summarizes the research activities on radiation-induced late effects in the rat spinal cord carried out within the "clinical research group ion beam therapy" funded by the German Research Foundation (DFG, KFO 214). METHODS AND MATERIALS Dose-response curves for the endpoint radiation-induced myelopathy were determined at 6 different positions (LET 16-99 keV/μm) wit...

The amount of information in the field of neurosurgery can be overwhelming. The following materials have been prepared for use as guidelines. While this may not be all-encompassing, it provides good guidelines and a foundation for further learning. XIII. Inflammatory disorders (multiple sclerosis, transverse myelopathy – learned in neurology rotation) XIV. Degenerative diseases (brain: dementia...