UNLABELLED Myxoedema madness was first described as a consequence of severe hypothyroidism in 1949. Most cases were secondary to long-standing untreated primary hypothyroidism. We present the first reported case of iatrogenic myxoedema madness following radioactive iodine ablation for Graves' disease, with a second concurrent diagnosis of primary hyperaldosteronism. A 29-year-old woman presente...

INTRODUCTION The distant metastases from differentiated thyroid carcinomas are often untreatable. In particular, bone metastasis is significantly related to poor prognosis since radioactive iodine therapy is generally less effective. Therefore, surgical resection is considered one of the treatments for patients with bone metastases. We report chest wall resection and reconstruction using titani...

introduction: recombinant human thyroid-stimulating hormone(rhtsh) increases radioactive iodine uptake(raiu) in selected populations, while lithium is used as an adjunct to radioactive iodine (rai) therapy in graves’ disease with low raiu. in this report, both drugs used in combination, overcame low iodine-131 uptake in a graves’ patient. clinical case: a 39-year old female with graves’ disease...

OBJECTIVE The prognostic values of serum thyroglobulin (Tg) and antithyroglobulin antibody (TgAb) levels, measured immediately before I-131remnant ablation in patients with differentiated thyroid cancer (DTC), have been advocated by some researchers; however, it had controversial outcomes. This study was carried out to examine this dilemma and to check the clinical significance of basal serum T...

Background. Conventional management of thyrotoxicosis includes antithyroid drugs, radioactive iodine, and surgery while adjunctive treatment includes beta-blockers, corticosteroids, inorganic iodide and iopanoic acid. Very rarely, patients may be resistant to these modalities and require additional management. Case Presentation. A 50-year-old lady presented with weight loss and palpitations dia...

Introduction: Various iodine isotopes are undergoing radioactive decay except Iodine-127 (I-127. Iodine I-131 is unsealed radioactive material used in nuclear medicine for both diagnostic and therapeutic procedures in Royal Hospital since 2006. In radiotoxic classification, I-131 is in group 2 element. I-131 is highly reactive element due to its volatilization nature. Currently...

The standard therapy for thyroid cancer is total or near total thyroidectomy, followed by the administration of radioactive iodine for remnant ablation or residual disease. Patients with radioiodine therapy are predisposed to second malignant neoplasms in organs such as central nervous system (CNS), breast, prostate, kidney, bone marrow, salivary gland, and digestive tract. Exposure to carcinog...

Introduction: Nowadays, radioisotopes have a lot of therapeutic and diagnostic applications in nuclear medicine. The technetium-99m radioisotope is widely used in the diagnostic field. The technetium-99m radioisotope is widely used in the diagnostic field. In this study, in order to increase the absorption dose in thyroid cancer cells, the radioactive drug technetium-99m which ...

Preliminary treatment with carbimazole in a series of 181 patients with thyrotoxicosis selected for treatment with radioactive iodine did not make any significant difference to the subsequent response to (131)I therapy.

Hypothyroidism is the most common disorder of thyroid dysfunction. Sometimes, it can be caused by a variety of medical treatments that leads to a decrease in thyroidal production and secretion of thyroxine and triiodothyronine. Radiation treatment, either radioactive iodine treatment of hyperthyroidism or external radiation treatment for cancer therapy is a major cause of treatment related hypo...