Patterns of fecal radioiodine excretion were studied in seven normal young men with intact, unblocked thyroid glands, who received repeated oral daily doses of [125I]iodide in an attempt to achieve isotopic equilibrium. Fecal radioactivity was assumed to have originated either in the circulating inorganic radioiodine (radioiodide) compartment or in the circulating hormonal protein-bound iodine ...

OBJECTIVES/HYPOTHESIS The purpose of this study is to review our experience with sialendoscopy for the management of radioiodine-induced sialadenitis. METHODS Retrospective chart review of all patients with radioiodine-induced sialadenitis treated with interventional sialendoscopy. RESULTS Twelve female patients with a mean age of 46.5 years (range, 25-77 years) underwent interventional sia...

BACKGROUND/AIM The aim of this study was to document the effect of the application of prophylactic central compartment dissection on radioiodine ablation activities for papillary thyroid carcinoma. MATERIALS AND METHODS This retrospective study included 452 (383 females, 69 males; mean age = 46.69 years, min-max: 13-71) patients who received ablative radioiodine activity between April 2010 an...

Ten cases of Ménétrier's disease (;giant hypertrophic gastritis') have been studied with radioiodine-labelled albumin (all 10 cases), IgG (eight cases), transferrin (two cases), and IgM (six cases). Abnormal gastric loss of plasma protein was present in all cases as demonstrated by (59)Fe-iron dextran (eight cases), (51)Cr-albumin (one case), and (131)I-polyvinylpyrrolidone (one case). None of ...

OBJECTIVE Patients with thyroid cancer may require detailed anatomic imaging before 131I therapy. Imaging by contrast-enhanced CT is contraindicated because it may result in saturation of tissues with iodine, decreasing the avidity of thyroid or thyroid cancer cells to subsequent radioiodine for extended intervals. Gadolinium-enhanced MRI offers an alternative to CT for detailed anatomic imagin...

radioiodine therapy is the safest, simplest, least expensive and most effective method for treatment of hyperthyroidism. the method employed in this research was a systematic bibliographic review, in which only valid studies or the clinically detailed enough open-labeled studies using validated scales were used. iodine-131 (i-131) acts by the destructive effect of short-range beta radiation on ...

Selective iodide uptake and prolonged iodine retention in the thyroid is the basis for targeted radioiodine therapy for thyroid cancer patients; however, salivary gland dysfunction is the most frequent nonthyroidal complications. In this study, we have used noninvasive single photon emission computed tomography functional imaging to quantify the temporal dynamics of thyroidal and salivary radio...

PURPOSE This retrospective study was aimed at revealing the safety and short-term outcome of radioiodine treatment in patients with Graves' disease at outpatient clinic. METHODS From July 1999 to April 2002, 511 patients with Graves' disease were treated with radioiodine at the outpatient clinic of Tajiri Thyroid Clinic, Kumamoto. Of them, 73 patients dropped out or were referred to another m...

Diagnostic and therapeutic use of radioiodine in the management of thyroid disorders depends on the ability of thyroid cells to concentrate radioiodine, a process that is regulated by the intracellular increase in cAMP. We hypothesized that theophylline, a drug known to increase intracellular cAMP via inhibition of phosphodiesterase, could increase thyroidal radioiodine uptake. We tested this e...

OBJECTIVE To assess the predictability of outcome and evaluate the factors that may lead to treatment failure in patients with Graves' disease who are treated with a single dose of radioiodine. MATERIALS AND METHODS This is a retrospective study of 123 patients (M: 42; F: 81) with Graves' disease who received radioiodine therapy with a single fixed (10 mCi) dose for hyperthyroidism. Pretreatm...