Training in the responsible conduct of research (RCR) is required for many research trainees nationwide, but little is known about its effectiveness. For a preliminary assessment of the effectiveness of a short-term course in RCR, medical students participating in an NIH-funded summer research program at the University of California, San Diego (UCSD) were surveyed using an instrument developed ...

The stream cipher TPypy has been designed by Biham and Seberry in January 2007 as the strongest member of the Py-family ciphers, after weaknesses in the other members Py, Pypy, Py6 were discovered. One main contribution of the paper is the detection of related-key weaknesses in the Py-family of ciphers including the strongest member TPypy. Under related keys, we show a distinguishing attack on ...

Detailed surface photometry has been carried out for three barred galaxies with use of high resolution CCD broadband images in the B, V and I bands. Using azimuthal luminosity profiles and their decomposition into Fourier Series, the structural parameters (length and strength) of the bars in the three galaxies have been obtained. We have also inferred the corotation radii (CR) using information...

Replication-competent retrovirus (RCR) vectors are intrinsically incapable of infecting quiescent cells and have been shown to achieve highly efficient and tumor-restricted replicative spread and gene transfer in vivo after direct intratumoral injection in a variety of primary cancer models. However, i.v. delivery of RCR vectors expressing therapeutic genes has never previously been tested, par...

Analytical models were developed and simulations of memory latency were performed for Uniform Memory Access (UMA), Non-Uniform Memory Access (NUMA), Local-RemoteGlobal (LRG), and RCR architectures for hit rates from 0.1 to 0.9 in steps of 0.1, memory access times of 10 to 100 ns, proportions of read/write access from 0.01 to 0.1, and block sizes of 8 to 64 words. The RCR architecture provides f...

This paper analyzes the scaling window of a random CSP model (i.e. model RB) for which we can identify the threshold points exactly, denoted by rcr or pcr. For this model, we establish the scaling window W (n, δ) = (r − (n, δ), r+(n, δ)) such that the probability of a random instance being satisfiable is greater than 1 − δ for r < r − (n, δ) and is less than δ for r > r+(n, δ). Specifically, we...

The metabolic clearance rate (MCR) and renal clearance rate (RCR) of human chorionic gonadotropin (hCG) were measured in healthy young men and women using techniques of continuous intravenous infusion and rapid intravenous injection of unlabeled, highly purified hCG. Seven subjects received 4 d of infusion at a rate of 0.2 microgram/min, followed by an additional 4 d of infusion at 0.8 microgra...

The critical nuclear charge Zcr and the critical distance Rcr in the system of two colliding heavy nuclei—they are defined as those at which the ground-state level of the electron spectrum descends to the boundary of the lower continuum, with the result that beyond them (that is, for Z > Zcr or R < Rcr) spontaneous positron production from a vacuum becomes possible—are important parameters in t...

The influence of scientific publications is increasingly assessed using quantitative approaches, but most available metrics have limitations that hamper their utility [1]. Hutchins and colleagues recently proposed the Relative Citation Ratio (RCR) [2], which compares the citation rate of an article against the citation rate that is expected for its field. The metric is an attractive and intuiti...

The value of responsible conduct of research (RCR) education from an administrative perspective can be summed up in the oft-used adage, an ounce of prevention is worth a pound of cure. The National Academy of Sciences has underscored the importance of RCR education in three major reports relating public trust in research to the perception and reality of integrity within the field. Compliance an...