نتایج جستجو برای: reactivators
تعداد نتایج: 133 فیلتر نتایج به سال:
In this study, several thin-layer chromatography (TLC) methods are described for the identification of quaternary and non-quaternary compounds (parent compounds, intermediates, by-products, and products) arisen within the synthesis of the acetylcholinesterase reactivator HI-6, at present the most promising antidote in the case of nerve agent poisonings. Using the TLC technique, particular E and...
Nerve agents belong to the most toxic organophosphates (OP) in the group of cholinesterase inhibitors. They can be used as chemical warfare agents and, they can be (and were) misused by terrorists, as happened in Matsumoto city (1994) and Tokyo subway (1995). Sarin was used in these cases. Medical protection against their effect (i.e. antidotal treatment) is of prime importance (Bajgar 2004, 20...
Frontline acute myeloid leukemia (AML) treatment is determined by a combination of patient and genetic factors. This includes fitness (i.e., comorbidities that increase the risk treatment-related mortality) characteristics, including cytogenetic events gene mutations. In older unfit patients, standard care typically venetoclax (VEN) combined with hypomethylating agents (HMA). Recently, several ...
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