CLINICAL CASE The case is presented of a 43 year-old male patient with chronic follicular conjunctivitis, negative bacterial serology, and refractory to local treatment. The incisional biopsy performed showed to be consistent with reactive lymphoid hyperplasia. A year later, a new incisional biopsy showed follicular lymphoma, with no systemic involvement, and he was treated with local radiother...

Malignant mesothelioma (MM) is the aggressive tumor of serosal surfaces. There are crude pathogenetic results regarding the biology of MM. Coordinated upregulations of p53 gene expression are shown in malignancies. We believed that there are changes in the p53 expression with transformation from reactive hyperplasia to MM. A 65-year-old male was admitted the hospital because of left pleuritic c...

Introduction. Currently, there are limited papers on changes in the pseudostratified ciliated columnar epithelium of sinonasal tract chronic inflammatory processes, particularly basal cell hyperplasia. The latter is similar to dysplasia varying severity stratified squamous nonkeratinized epithelium. Studying can clarify histogenesis various epithelial tumors tract, including papillomas. researc...

OBJECTIVE Reactive oxygen species are important mediators for platelet-derived growth factor (PDGF) signaling in vascular smooth muscle cells, whereas excess reactive oxygen species-induced oxidative stress contributes to the development and progression of vascular diseases, such as atherosclerosis. Activation of the redox-sensitive transcription factor, nuclear factor erythroid 2-related facto...

Pulmonary nodular lymphoid hyperplasia (PNLH) is a reactive lymphoid proliferation manifesting as multiple solitary nodules or localized infiltrates in the lungs. It is a type of benign lymphoproliferative disease that can affect the lungs. We present the case of a 41-year-old female patient with respiratory symptoms such as productive cough, left chest pain, and dyspnea. Imaging findings revea...

Repetitive topical applications of 2 micrograms 12-O-tetradecanoylphorbol-13-acetate (TPA) twice weekly for 37 to 52 weeks induced a sustained epidermal hyperplasia, hyperplasia of hair follicles, and increased dermal cellularity in SENCAR mice. In addition, after 52 weeks of protracted promoter treatment most animals developed generalized amyloidosis involving liver and spleen, as well as inte...

DIAGNOSIS: A. All that is papillary in the bladder is not papillary urothelial neoplasia: i. Diagnostic pitfalls: papillary hyperplasia, nephrogenic adenoma, fibroepithelial polyp and papillary/polypoid cystitis ii. Artifacts: pseudopapillary folds and avulsed urothelium B. All urothelial proliferations that expand the lamina propria are not invasive carcinoma: i. Diagnostic pitfalls: florid vo...

BACKGROUND In the literature, many studies were attempted to analyze the distribution of oral reactive lesions in terms of age, gender and location. However, very few studies have focused on the detailed histopathological features of these reactive lesions of oral cavity. Thus, the purpose of this paper is to document the occurrence, distribution and various histopathological features of reacti...