We have studied the effect of oxidant stress on human lymphocyte cytotoxicity. Lymphocyte cultures maintained good viability after incubation with xanthine and xanthine oxidase. an enzyme system known to generate several highly reactive oxygen compounds. We demonstrated that these lymphocytes were viable after exposure to an in vitro oxidant stress but had a significant impairment in both antib...

INTRODUCTION Peritonsillar abscess is a serious infectious disease of the tonsillar tissue. Treatment generally requires both medical and surgical approaches to relieve the symptoms. Recently, in addition to clinical follow-up, some inflammatory markers, such as the mean platelet volume and neutrophil-to-lymphocyte ratio, have been considered to be additional inflammatory monitoring markers in ...

BACKGROUND No previous clinical study has been designed to assess the additive effect of metformin and a fibrate on lymphocyte secretory function. The aim of our study was to investigate whether metformin produces any effect on lymphocyte cytokine release in fibrate-treated patients with early glucose metabolism abnormalities. METHODS The study included 80 patients with isolated impaired gluc...

STUDY DESIGN A case-control study. OBJECTIVE The objective of this study is to identify biochemical markers for surgical site infection (SSI) in posterior instrumented spinal fusion that are not affected by operative circumstances and to determine diagnostic cutoffs for these markers. SUMMARY OF BACKGROUND DATA Numerous biochemical markers may be used for early detection of SSI; however, th...

Objective: The present study aimed to evaluate the prognostic importance of hematologic test findings in addition neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte monocyte-to-lymphocyte systemic inflammation response index, and C-reactive protein patients with deep neck infection compare these results healthy subjects.Material Methods: included 32 diagnosed as treated by surgical interven...

A new method was developed for detection of monoclonality at the DNA level in B-lymphoproliferative disease using the polymerase chain reaction and consensus primers for the V and J regions of the immunoglobulin gene. Monoclonality was detected in DNA from 15 of 15 clonal B-lymphoblastoid cell lines and from 19 of 23 cases of B-lymphocyte neoplasia, but not from any of 16 normal T-lymphocyte cl...

Objective: Psoriasis is a chronic inflammatory disease and clinical symptoms start during childhood in about one third of the patients. The aim this study to investigate existence inexpensive easily applicable laboratory parameters that can be used evaluation activity severity psoriasis. Material Methods: This retrospective included 72 psoriatic patients who admitted dermatology outpatient clin...

We have investigated the regulation of self tolerance in mice by examining lymphocyte reactivity in vitro against two subpopulations of autologous testicular cells: germ cells that were derived from the seminiferous tubules, and interstitial somatic cells. In the presence of germ cells, lymphocyte proliferation was strongly reduced. In contrast, somatic interstitial cells stimulated lymphocyte ...

INTRODUCTION: This study was designed to compare the immature granulocyte (IG) count, IG-to-lymphocyte ratio (IGLR), complete blood count (CBC) values, and inflammatory parameters of neutrophil-to-lymphocyte (NLR), platelet-to-lymphocyte (PLR), C-reactive protein (CRP), ferritin level, CRP-to-albumin (CAR) measured at hospital admission in patients with coronavirus disease 2019 (COVID-19) non-C...