Genome-wide association studies have successfully identified hundreds of novel genetic variants associated with many complex human diseases. However, there is a lack of rigorous work on evaluating the statistical power for identifying these variants. In this paper, we consider sparse signal identification in genome-wide association studies and present two analytical frameworks for detailed anal...

During automated process execution semantic activity failures may frequently occur, e.g., when a vehicle transporting a container has a breakdown. So far there are no applicable solutions to overcome such exceptional situations. Often the only possibility is to cancel and roll back respective process instances what is not always possible and more often not desired. In this paper we contribute t...

In an organization, a well devised disaster recovery plan is not only crucial in the information recovery process, but also vital in the quest to sustain daily operations. While prior research has discussed many recovery sites options, assessment of recovery site communication paths and their associated complexity is still limited in regard to the evaluation of disaster recovery (DR) models. Us...

the main idea of this paper is to study the dependence between the probability of default and the recovery rate on credit portfolio and to seek empirically this relationship. we examine the dependence between pd and rr by theoretical approach. for the empirically methodology, we use the bootstrapped quantile regression and the simultaneous quantile regression. these methods allow to determinate...

A liquid chromatographic (LC) method is described for determination of total vitamin B6 in soy-based infant formula. Total vitamin B6 is quantitated by using ion-pair LC after precolumn transformation of phosphorylated and free vitamers into pyridoxol. The limit of detection is 0.3 ng and the limit of quantitation is 1.0 ng on-column (injection volume = 100 microL). Linear response ranged from ...

Melamine is a nitrogen-rich industrial chemical which is occasionally used to increase the apparent protein content of different products destined for human and animal consumption. In this work, a liquid chromatographic procedure that uses micellar mobile phases of sodium dodecyl sulfate (SDS) buffered at pH 3, a C18 column and UV detection is reported for the determination of melamine in diete...

Beta-galactooligosaccharides (GOS) are oligosaccharides normally produced industrially by transgalactosylation of lactose. They are also present naturally in the milk of many animals including humans and cows. GOS are thought to be good for health, being potential prebiotic fibres, and are increasingly added to food products. In order to control the GOS content of products, the AOAC official me...

Choline was determined in infant formula by ion chromatography with suppressed conductivity detection. Samples were digested with 1M hydrochloric acid, filtered, diluted, and injected into the chromatographic system. Choline and the alkali and alkaline earth metals were separated on a high-resolution cation-exchange column and detected by suppressed conductivity. The method was linear between 2...

This article provides a simple and general way for defining the recovery rate of clustering algorithms using a given family of old clusters for evaluating the performance of the algorithm when calculating a family of new clusters. Under the assumption of dealing with simulated data (i.e., known old clusters), the recovery rate is calculated using one proposed exact (but slow) algorithm, or one ...