نتایج جستجو برای: recurrent breast cancer

تعداد نتایج: 1093634  

2010
Leiddy Z. Alvarado Narasimhamurthy Shanaiah G. A. Nagana Gowda Robert A. Ballas Daniel Raftery

Downlo report on the development of a monitoring test for recurrent breast cancer, using metaboliteng methods. Using a combination of nuclear magnetic resonance (NMR) and two-dimensional gas atography–mass spectrometry (GC×GC-MS) methods, we analyzed the metabolite profiles of 257 retrove serial serum samples from 56 previously diagnosed and surgically treated breast cancer patients. One ed six...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2009
O Dizdar S Aksoy K Altundag

We read with great interest the article by Largillier et al. [1] in which they analyzed prognostic factors in 1038 women with metastatic breast cancer. They did not show the importance of metastasis-free interval as a prognostic factor predicting survival from time of metastatic occurrence in their studies on contrary to other studies stating that early recurrence is an independent predictor of...

2014
Katherine E. Varley Jason Gertz Brian S. Roberts Nicholas S. Davis Kevin M. Bowling Marie K. Kirby Amy S. Nesmith Patsy G. Oliver William E. Grizzle Andres Forero Donald J. Buchsbaum Albert F. LoBuglio Richard M. Myers

Read-through fusion transcripts that result from the splicing of two adjacent genes in the same coding orientation are a recently discovered type of chimeric RNA. We sought to determine if read-through fusion transcripts exist in breast cancer. We performed paired-end RNA-seq of 168 breast samples, including 28 breast cancer cell lines, 42 triple negative breast cancer primary tumors, 42 estrog...

Journal: :Oncology nursing forum 2002
Laurel L Northouse Julie Walker Ann Schafenacker Darlene Mood Suzanne Mellon Elizabeth Galvin Janet Harden Laurie Freeman-Gibb

PURPOSE/OBJECTIVES To evaluate the FOCUS Program (family involvement, optimistic attitude, coping effectiveness, uncertainty reduction, and symptom management), a family-based program of care for women with recurrent breast cancer and their family caregivers. DATA SOURCES Randomized clinical trial. SETTING Midwest region of the United States. DATA SYNTHESIS The family-based program of car...

2014
Yoshihiro Shioi Masahiro Kashiwaba Toru Inaba Hideaki Komatsu Tamotsu Sugai Go Wakabayashi

PATIENT Female, 56 FINAL DIAGNOSIS: Breast cancer Symptoms: Solid mass in the right breast Medication: Exemestane Clinical Procedure: - Specialty: Oncology. OBJECTIVE Unusual clinical course. BACKGROUND The efficacy of third-generation aromatase inhibitors for hormone receptor-positive postmenopausal metastatic breast cancer is well established. Although several clinical trials have reporte...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2015
Gabriela Torres-Mejía Robert Royer Marcia Llacuachaqui Mohammad R Akbari Anna R Giuliano Louis Martínez-Matsushita Angélica Angeles-Llerenas Carolina Ortega-Olvera Elad Ziv Eduardo Lazcano-Ponce Catherine M Phelan Steven A Narod

BACKGROUND Germline mutations in the BRCA1 and BRCA2 genes confer an estimated 58% to 80% lifetime risk of breast cancer. In general, screening is done for cancer patients if a relative has been diagnosed with breast or ovarian cancer. There are few data on the prevalence of mutations in these genes in Mexican women with breast cancer and this hampers efforts to develop screening policies in Me...

2014
Handan Tokmak Kerim Kaban Mahmut Muslumanoglu Meral Demirel Sukru Aktan

BACKGROUND In patients with recurrent or second primary ipsilateral breast cancer, axillary staging is the key factor in locoregional control and a strong prognostic characteristic. The efficient evaluation of lymphatic drainage of re-sentinel lymph node biopsies (re-SLNBs) has remained a challenge in the management of ipsilateral primary or recurrent breast cancer patients who are clinically l...

2018
Chen Chi Leigh C. Murphy Pingzhao Hu

Breast cancer diagnosis in young women has emerged as an independent prognostic factor with higher recurrence risk and death than their older counterparts. We aim to find recurrent somatic copy number alteration (CNA) regions identified from breast cancer microarray data and associate the CNA status of the genes harbored in the regions to the survival of young women with breast cancer. By using...

Journal: :Cancer research 2005
John W M Martens Inko Nimmrich Thomas Koenig Maxime P Look Nadia Harbeck Fabian Model Antje Kluth Joan Bolt-de Vries Anieta M Sieuwerts Henk Portengen Marion E Meijer-Van Gelder Christian Piepenbrock Alexander Olek Heinz Höfler Marion Kiechle Jan G M Klijn Manfred Schmitt Sabine Maier John A Foekens

To understand the biological basis of resistance to endocrine therapy is of utmost importance in patients with steroid hormone receptor-positive breast cancer. Not only will this allow us prediction of therapy success, it may also lead to novel therapies for patients resistant to current endocrine therapy. DNA methylation in the promoter regions of genes is a prominent epigenetic gene silencing...

2014
Ania W. Payne Dhruv K. Pant Tien-Chi Pan Lewis A. Chodosh

Recurrent breast cancer is typically an incurable disease and, as such, is disproportionately responsible for deaths from this disease. Recurrent breast cancers arise from the pool of disseminated tumor cells (DTC) that survive adjuvant or neoadjuvant therapy, and patientswith detectableDTCs following therapy are at substantially increased risk for recurrence. Consequently, the identification o...

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