With the rapid rate of adoption by farmers worldwide of crop varieties containing multiple value-added traits, mainly genetically modified traits, as many as 15 to 20 transgenic events may be offered in new maize hybrids by 2030 (Que et al. 2010; Fraley 2012). Multiple Trait Integration (MTI) is designed to integrate the specific transgenic events conferring the value-added trait phenotypes int...

Individuals may experience more than one type of recurrent event and a terminal event during the life course of a disease. Follow-up may be interrupted for several reasons, including the end of a study, or patients lost to follow-up, which are non informative censoring events. Death could also stop the follow-up, hence, it is considered as a dependent terminal event. We propose a multivariate f...

We propose a semiparametric additive rate model for modelling recurrent events in the presence of a terminal event. The dependence between recurrent events and terminal event is nonparametric. A general transformation model is used to model the terminal event. We construct an estimating equation for parameter estimation and derive the asymptotic distributions of the proposed estimators. Simulat...

Recurrent events data have been increasingly important in clinical studies. There are many methods to analyze this type of data. Several papers have been presented about how to perform repeated events analysis in SAS. In clinical studies, we may encounter recurrent disease episodes in patients with a terminal event such as death, and the terminal event is often strongly correlated with the recu...

BACKGROUND The incidence of a first acute myocardial infarction (AMI) has fallen considerably during the last decades. However, no previous studies have analyzed the underlying hazards function of experiencing a recurrent AMI, and none has analyzed the change of risk for a recurrent AMI over the last 3 decades. METHODS AND RESULTS The study was based on the Swedish national myocardial infarct...

Event-history studies of recurrent events are often conducted in fields such as demography, epidemiology, medicine, and social sciences (Cook and Lawless, 2007, The Statistical Analysis of Recurrent Events. New York: Springer-Verlag; Zhao et al., 2011, Test 20, 1-42). For such analysis, two types of data have been extensively investigated: recurrent-event data and panel-count data. However, in ...

Background—The incidence of a first acute myocardial infarction (AMI) has fallen considerably during the last decades. However, no previous studies have analyzed the underlying hazards function of experienceing a recurrent AMI, and none has analyzed the change of risk for a recurrent AMI over the last 3 decades. Methods and Results—The study was based on the Swedish national myocardial infarcti...

RATIONALE there are several well-developed statistical methods for analysing recurrent events. Although there are guidelines for reporting the design and methodology of randomised controlled trials (RCTs), analysis guidelines do not exist to guide the analysis for RCTs with recurrent events. Application of statistical methods that do not account for recurrent events may provide erroneous result...