BACKGROUND Pterygium is a common problem and after surgical removal may recur in up to 80% of cases, depending on the technique of primary excision. Recurrent pterygia can be aggressive and repeated excision may result in severe conjunctival scarring and shortening, resulting in insufficient conjunctiva to perform further grafting and lid surgery. When there is insufficient autologous conjuncti...

Purpose: Randomised study to evaluate the role of Cyclosporine eye drops (0.05%) pre & postoperatively on recurrence in cases of recurrent & vascularized pterygium, undergoing excision and Conjunctival Limbal Autograft with Fibrin glue. Materials and Methods: In this prospective study 100 eyes of 100 patients were taken up for study in two groups – Group A (50 eyes) and Group B (50 eyes). Only ...

BACKGROUND To examine the immunohistochemical expression of heat shock protein 90 (Hsp90) and Ki-67 protein in human pterygium. MATERIALS AND METHODS Tissues obtained during pterygium surgery of 15 patients who underwent the bare-sclera procedure and 10 normal conjunctivae were studied. All of these pterygia were primary ones. Recurrent pterygia were excluded. Normal bulbar conjunctivas (2 x ...

The authors report the long-term results of combined conjunctival autograft and overlay amniotic membrane transplantation (AMT) for treatment of pterygium as a new surgical technique. Nineteen patients including 12 male and 7 female subjects with pterygium (primary, 14 cases; recurrent, 5 cases) underwent combined conjunctival autograft and overlay AMT and were followed from 10 to 26 months. Me...

Background & Objectives: Pterygium is a fibrovascular degeneration of the conjunctiva. Ocular surface squamous neoplasia encompasses wide spectrum dysplastic changes including corneal and conjunctival intraepithelial cell carcinoma. They both share common risk factors can coexist concomitantly. This study aims to determine association between OSSN pterygium which will help improve management pt...

PURPOSE The purpose of this study is to evaluate and compare recurrence rates upon using mitomycin C (MMC) with limbal-conjunctival autograft for treating recurrent pterygia. METHODOLOGY An interventional, prospective, comparative clinical study was performed in 30 eyes (26 patients) with recurrent pterygia, allocated into two groups: Group A (19 eyes) operated by pterygium excision and limba...

OBJECTIVE To assess the potential role of matrix metalloproteinases (MMPs) in the pathogenesis of pterygia by comparing the immunolocalization patterns of MMPs in altered limbal basal stem cells, activated fibroblasts, and areas of elastotic degeneration adjacent to the pterygia. METHODS Nine primary and 1 recurrent pterygia along with normal superior limbal-conjunctival tissue and cornea wer...

PURPOSE To compare various techniques of pterygium surgery including bare sclera, intraoperative mitomycin C application, conjunctival flap reconstruction, and conjunctival autografting technique. METHODS This study is designed to compare 4 currently used techniques in order to determine the complication and recurrence rates after pterygium exision. Included in the study were 77 eyes from 60 ...

Pterygium is a potentially vision-threatening fibrovascular lesion originating from the conjunctiva that often extends on the corneal surface. Although it has been extensively studied, its pathogenesis has yet to be fully elucidated. Recent evidence on molecular genetic abnormalities in pterygium suggested neoplastic changes of limbal stem cells potentially associated with exposure to ultraviol...