This paper overviews the present status on therapy of regenerative medicine which is based on tissue engineering. Tissue engineering is a biomedical form which enables cells to promote their proliferation and differentiation, resulting in induction of tissue regeneration. The scaffold of 3-dimensional porous material for cells with or without the controlled release system of growth factor is ap...

1 Laboratory of Stem Cells and Neuroregeneration, Institute of Anatomy, Histology and Pathology, Faculty of Medicine, Universidad Austral de Chile, Valdivia, Chile, Center for Interdisciplinary Studies on the Nervous System (CISNe), Universidad Austral de Chile, Valdivia, Chile, 3 Institute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria, 4 Spinal Cord Injur...

Stem cells are capable of renewing themselves through cell division and have the remarkable ability to differentiate into many different types of cells. They therefore have the potential to become a central tool in regenerative medicine. During the last decade, advances in tissue engineering and stem cell-based tooth regeneration have provided realistic and attractive means of replacing lost or...

Sofia G. Caridade, Esther G. Merino, Gisela M. Luz, Natália M. Alves, João F. Mano 1 3B's Research Group Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, 4806-909 Taipas, Guimarães, Portugal 2 IBB – Institute for Biotechnology and Bioengineering, PT Government Associa...

Regeneration is a common phenomenon across multiple animal phyla. Regeneration-related genes (REGs) are critical for fundamental cellular processes such as proliferation and differentiation. Identification of REGs and elucidating their functions may help to further develop effective treatment strategies in regenerative medicine. So far, REGs have been largely identified by small-scale experimen...

The present regenerative medicine needs more clear views on the use of various grow th factors. This present study reviewed important facts on the use of Fibroblast Growth Factors-2 (Fgf-2). Fgf-2 role on regenerative medicine especially with regards to inner hair cell regeneration from different stem cell source is needs to be well understood, because its function and activity on specific cell...

The vitality of the pulp is fundamental to the functional life of the tooth. For this aim, active and living biomaterials are required to avoid the current drastic treatment, which is the removal of all the cellular and molecular content regardless of its regenerative potential. The regeneration of the pulp tissue is the dream of many generations of dental surgeons and will revolutionize clinic...