Jonassen, Thomas E. N., Sten Christensen, Niels Marcussen, and Jørgen Søberg Petersen. Intrarenal octreotide treatment prevents sodium retention in liver cirrhotic rats: evidence for direct effects within the thick ascending limb of Henle’s loop. Am J Physiol Renal Physiol 291: F537–F545, 2006. First published January 17, 2006; doi:10.1152/ajprenal.00226.2005.—We have previously shown that syst...

Introduction: The selection of   optimal treatment of obstructive nephrouropathy requires information about the functional status of each kidney. Nuclear renal scanning objectively measure differential renal function, multiple studies have demonstrated the role of assessment of renal perfusion and GFR with triphasic CT. The aim of this study is to assess the role of CT based on renal parenchyma...

objective(s): nanosilver is one of the most widely used nanomaterials due to its strong antimicrobial activity. thus, because of increasing potential for exposure of human to nanosilver, there is an increasing concern about possible side effects of these nanoparticles. in this study, we tested the potential dermal toxicity of nanosilver bandage on serum chemical biomarkers in mice.  materials a...

background: eurycoma longifolia jack (elj) has been shown to elevate serum testosterone and increased muscle strength in humans. this study investigated the effects of physta® a standardized water extract of elj (400 mg/day for 6 weeks) on testosterone: epitestosterone (t:e) ratio, liver and renal functions in male recreational athletes. methods: a total of 13 healthy male recreational athletes...

We report the case of a 69-year-old woman with seizures and acute renal failure with hyperkalemia. She presented with bladder turgescence and hydronephrosis on admission and was diagnosed as obstructive acute renal failure. Urethral catheterization was performed after a single-session hemodialysis. It resulted in immediate improvement of renal function and consciousness, and subsequent disappea...

We previously reported that inappropriate renal vasoconstriction in Dahl salt-sensitive (DS) rats fed high NaCl diets may cause sodium retention. The present study examined the distribution and elimination of Na in DS and Dahl salt-resistant (DR) rats, and we determined whether an abnormality in renal function might also cause sodium retention in DS rats. Following an intravenous bolus of 4 mCi...

We previously reported that inappropriate renal vasoconstriction in Dahl salt-sensitive (DS) rats fed high NaCl diets may cause sodium retention. The present study examined the distribution and elimination of 22Na in DS and Dahl salt-resistant (DR) rats, and we determined whether an abnormality in renal function might also cause sodium retention in DS rats. Following an intravenous bolus of 4 m...

Background Volume overload and sodium retention in congestive heart failure (HF) are usually treated with loop diuretics. However, worsening renal function is frequently observed and is associated with worse outcomes. Soluble guanylyl cyclase (sGC) plays an important role in renal function. Importantly, sGC activation can be impaired in cardiorenal disease states, which can be due to not only d...