It is thought that cardiovascular changes may contribute to sudden death in patients with epilepsy. To examine cardiovascular alterations that occur during epileptogenesis, we measured the heart rate of rats submitted to the electrical amygdala kindling model. Heart rate was recorded before, during, and after the induced seizures. Resting heart rate was increased in stages 1, 3, and 5 as compar...

Tore Sørlie Psychiatry Research Group Institute of Clinical Medicine Faculty of Health Sciences University of Tromsø and Clinic for General Psychiatry University Hospital of Northern Norway A man in his forties had been repeatedly assessed over a period of 15 years at neurological departments and specialised epilepsy hospitals. The conclusion was always psychogenic, non-epileptic seizures (PNES...

PURPOSE To report the effectiveness and safety of intravenous levetiracetam in the treatment of children with acute repeated seizures, and status epilepticus in a children's hospital. METHODS This two-year observational study evaluated all in-patients who received intravenous levetiracetam to treat acute repeated seizures (ARS) or convulsive and non-convulsive status epilepticus (SE). Informa...

Regarding the therapeutic properties of Nigella sativa (NS), the effects of the plant hydro – alcoholic extract on learning, memory and brain tissues oxidative damage were investigated in penthylenetetrazole (PTZ) - induced repeated seizures.There were 4 experimental groups including: 1- control group; received saline, 2- PTZ group ; received saline and PTZ (50 mg/kg, i.p) , 3-PTZ- NS 200 and 4...

Regarding the therapeutic properties of Nigella sativa (NS), the effects of the plant hydro – alcoholic extract on learning, memory and brain tissues oxidative damage were investigated in penthylenetetrazole (PTZ) - induced repeated seizures.There were 4 experimental groups including: 1- control group; received saline, 2- PTZ group ; received saline and PTZ (50 mg/kg, i.p) , 3-PTZ- NS 200 and 4...

Although general guidelines exist for the diagnosis and the treatment of epilepsy, no specific recommendations are available concerning the management of seizures related to cerebrovascular disease. The incidence of seizures after stroke was found to be 8.9% in the only published prospective study. This is an underestimation as seizures occurring at stroke onset were not taken in to account and...

Exposition to the acute intensive hypobaric hypoxia blocks the triggering mechanism of epileptic seizures only within a short time interval after the end of hypoxia period and it does not influence the progressive epileptogenesis in 12-day-old rats. In 25-day-old rats' hypobaric hypoxia suppresses the postictal depression elicited by the repeated stimulation in short interstimulus intervals and...

brain tumors are considered in regarded to their size, position and aggressive manner. brain tumors cause several neurologic symptoms. for instance, they increase intracranial pressure due to local damage and displacement of surrounding tissues. in this paper, two glioblastoma multiform cases with more than 15 year- survival have been reported. the first patient was a 52 year- old woman who suf...