Tight junctions (TJs) are protein complexes comprised of claudins, which anchor them in the membrane and numerous cytosolic scaffolding proteins including MAGI, MUPP1, cingulin and members of the Zonula Occludens (ZO) family. Originally, their main function was thought to be as a paracellular barrier. More recently, however, additional roles in signal transduction, differentiation and prolifera...

In the 1960s and 1970s the Italian born scientist Antonio Priore, working in France, amazed the public and divided the scientific world with his invention, a machine which could cure a variety of illnesses, including cancer. Gaining the support of the French government and several scientific organizations, Priore received a great amount of money in funds to sustain his research. Without exposin...

In autumn 1726, Mary Toft began to deliver rabbits in Godalming, Surrey. The case became a sensation and was reported widely in newspapers, popular pamphlets, poems and caricatures. Toft was attended by at least six different doctors, some members of the Royal College of Physicians or attached to the Royal Court, but no doctor declared the affair a hoax until Toft herself confessed on 7 Decembe...

Love, attachment, and truth of human monogamy have become important research themes in neuroscience. After the introduction of functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET), neuroscientists have demonstrated increased interest in the neurobiology and neurochemistry of emotions, including love and affection. Neurobiologists have studied pair-bonding mechanis...

(Fortini and Artavanis-Tsakonas, 1994), or that activation Poulson first described Drosophila embryos that lacked brings about proteolytic cleavage of Notch, so that an Notch function in 1937 (Poulson, 1937), referring to them intracellular portion of Notch itself moves to the nucleus as “a kind of hopeless monster.” Half a century later it and collaborates with CSL to activate transcription (K...

lN MAY, 1971 THE SINGAPORE GOVERNMENT CAUSED AN ENGLISHlanguage newspaper, The Singapore Herald, to cease publication. Although its circulation was considerably less than the long-established Straits Times, in its year of existence the Herald had gained many loyal readers. They looked to the Herald for balU?ced, critical commentary on national affairs, something rarely found in the Times, at le...

Abstract This essay, a product of reflection and dialogue between Palestinian Jewish Israeli, revisits the so-called "Teddy Katz Affair," heated debate that erupted first in 2000 but resurfaced recently due to new documentary. The Affair was triggered by newspaper article reporting about master’s thesis, which relied heavily on oral testimonies, concluded war crimes against Palestinians were co...