Objective(s):Multidrug resistance (MDR) of cancer cells is a major obstacle to successful chemotherapy. Overexpression of breast cancer resistance protein (BCRP) is one of the major causes of MDR. In addition, it has been shown that PI3K/Akt signaling pathway involves in drug resistance. Therefore, we evaluated the effects of novel approaches including siRNA directed against BCRP and targeted t...

single-phase squirrel cage and three-phase induction electromotors are the most popular electromotors used in industry from long ago. when an induction motor starts with direct connection method, it takes a lot of current from the power supply (several times the nominal current); so, several methods have been devised to start such electromotors. these methods either reduce the voltage of the st...

This paper presents a detailed study of the extended Kalman filter (EKF) for estimating the rotor resistance and rotor speed of an induction motor drive. The overall structure of the EKF is reviewed and the various system vectors and matrices are defined. By including the rotor resistance and rotor speed as a state variables, the EKF equations are established from a discrete two-axis model of t...

Induction of resistance to macrolide-, lincosamide-, and streptogramin B-type antibiotics in Staphylococcus aureus was studied by monitoring the appearance of erythromycin A (EM)-resistant [(14)C]leucine incorporation. Examination of the induction process revealed saturation kinetics and a time course much like that reported for penicillinase in gram-positive bacteria. Induction kinetics in exp...

Induction of resistance to macrolide-, lincosamide-, and streptogramin B-type antibiotics in Staphylococcus aureus was studied by monitoring the appearance of erythromycin A (EM)-resistant [14C]leucine incorporation. Examination of the induction process revealed saturation kinetics and a time course much like that reported for penicillinase in gram-positive bacteria. Induction kinetics in expon...