Variant viruses mutated in the immunodominant cytotoxic T cell epitope surface (S) glycoprotein S-510-518 are selected in mice chronically infected with mouse hepatitis virus, strain JHM. We determined whether this selection occurred in the presence of an oligoclonal or polyclonal T cell response using soluble MHC/peptide tetramers in direct ex vivo analyses of CNS-derived lymphocytes. A total ...

[3H]palmitic acid was metabolically incorporated into the viral fusion protein (F) of Edmonston or freshly isolated measles virus (MV) during infection of human lymphoid or Vero cells. The uncleaved precursor F0 and the F1 subunit from infected cells and extracellular virus were both labeled, indicating that palmitoylation can take place prior to F0 cleavage and that palmitoylated F protein was...

A novel fluorescent probe 1 is reported here with ratiometric response to hydrophobic proteins (casein) or proteins with hydrophobic pockets (BSA, HSA) through hydrophobic interaction. Probe 1 underwent deprotonation in aqueous solution at pH 7.4 and emitted blue fluorescence at 436 nm. Upon the addition of BSA, HSA or casein, the aggregation-induced emission fluorescence of 1 at 518 nm was tur...

[This corrects the article on p. 518 in vol. 7, PMID: 27148207.].

0968-090X/$ see front matter 2013 Elsevier Ltd. All rights reserved. http://dx.doi.org/10.1016/j.trc.2013.06.018 q This paper was presented at the 20th International Symposium on Transportation & Traffic Theory. It therefore also appears in the complete pro of the 20th ISTTT in [Procedia – Social and Behavioral Sciences, vol. 80C (2013), pp. 473–490]. ⇑ Corresponding author. Tel.: +1 518 276 80...

The endothelin antagonist BQ-123, an anionic cyclopentapeptide, is taken up by rat hepatocytes through active transport systems. Here, we have examined the hepatocellular uptake mechanism for several BQ-123 derivatives with anionic charges using isolated rat hepatocytes. BQ-485, a linear peptide, BQ-518, a cyclic peptide, and compound A, a cyclic peptide with a cationic moiety, were taken up by...

Global Institute for Health and Human Rights (GIHHR), University at Albany, New York, United States Department of Public Administration and Policy, Rockefeller College, University at Albany, New York, United States School of Criminal Justice, University at Albany, New York, United States Department of Health Policy, Management and Behavior, School of Public Health, University at Albany, New Yor...

The Gleason grading system is a fundamental indicator of the aggressive nature of prostate cancer (PCa). Diffusion-weighted imaging (DWI) and magnetic resonance (MR) spectroscopy (MRS) are methods for the assessment of PCa aggressiveness. The present study was designed to prospectively investigate whether transrectal ultrasound (TRUS)-guided MR imaging (MRI)-directed biopsies (TRUS‑MR‑Dbs) impr...

investigation of inheritance, mode of gene action and determination of effective breeding strategy for improvement of physiological and morpho-physiological traits specifically in drought stress conditions is very important. to determine the inheritance pattern and genetic parameters of quantitative characters in bread wheat (triticum aestivum), p1, p2, bc1, bc2, f1, f2 generations derived from...