Bovine respiratory syncytial virus (BRSV) is a major cause of respiratory disease and a major contributor to the bovine respiratory disease (BRD) complex. BRSV infects the upper and lower respiratory tract and is shed in nasal secretions. The close relatedness of BRSV to human respiratory syncytial virus (HRSV) has allowed researchers to use BRSV and HRSV to elucidate the mechanisms by which th...

Respiratory syncytial virus (RSV) is a common winter time respiratory virus that affects persons of all ages. RSV was first isolated in children with pulmonary disease in 1957. Initially referred to as the ‘chimp coryza virus’, the nature of the virus to form syncytia (fusion of cells to form larger cells without any internal cell boundaries) in tissue culture subsequently resulted in the virus...

background and aims: respiratory syncytial virus (rsv) infection is common in infants and young children. in infants younger than one year old it may cause bronchiolitis and pneumonia which requires hospitalization. accurate and rapid diagnosis of the disease will help proper treatment of the disease and prevent further complications. materials and methods: specimen taken from respiratory tract...

This study aimed to quantify the effect of age, time since last infection, and infection history on the rate of respiratory syncytial virus infection and the effect of age and infection history on the risk of respiratory syncytial virus disease. A birth cohort of 635 children in Kilifi, Kenya, was monitored for respiratory syncytial virus infections from January 31, 2002, to April 22, 2005. Pre...

This study aimed to quantify the effect of age, time since last infection, and infection history on the rate of respiratory syncytial virus infection and the effect of age and infection history on the risk of respiratory syncytial virus disease. A birth cohort of 635 children in Kilifi, Kenya, was monitored for respiratory syncytial virus infections from January 31, 2002, to April 22, 2005. Pre...

At a recent workshop on infection the indications for ribavirin were discussed. Ribavirin has recently been licensed for hospital use in the United Kingdom having previously been available only on a named patient basis. Nebulised ribavirin is being vigorously promoted by the United Kingdom marketing company, Brittania Pharmaceuticals, for selected use in respiratory syncytial virus infections l...

with severe respiratory syncytial virus infection. Crit Care Med 1987;15:1051-4. 13 Gelfand EW, McCurdy D, Pandu Rao C, Middleton PJ. Ribavirin treatment of viral pneumonitis in severe combined immunodeficiency disease. Lancet 1983;ii:732-3. 14 McIntosh K, Kurachek SC, Cairns LM, Burns JC, Goodspeed B. Treatment of respiratory viral infection in an immunodeficient infant with ribavirin aerosol....

A complete genome of human respiratory syncytial virus was sequenced and analyzed. Phylogenetic analysis showed that the full-length human respiratory syncytial virus (HRSV) genome sequence belongs to gene type NA1. We sequenced the genome in order to create the full-length cDNA infectious clone and develop vaccines against HRSV.