To the Editor
 An elegant study reported dysmorphic cells and syncytia in deceased's lungs for COVID-19. The authors reasonably considered that most of these syncytia-forming were pneumocytes, as identified by specific biomarkers. However, cellular dysmorphism are pathological features common other respiratory infections caused different viruses, including human syncytial virus (HRSV) Epst...

respiratory syncytial virus infection in immunocompromised patients, especially those with defects in cell mediated immunity is associated with high morbidity and mortality. lymphocytopenia is an important factor associated with progression of upper to lower respiratory tract infection. the only licensed antiviral treatment for rsv available currently is ribavirin, although additional immunomod...

Respiratory syncytial virus is a major cause of respiratory disease. There are conflicting accounts of the response of human epithelial cells to respiratory syncytial virus and a lack of data on its effect on ciliary function. Our aim was to study the early stages of respiratory syncytial virus infection of primary human basal and ciliated cultures. Using high speed videomicroscopy, we found th...

An investigation was made on the effect of acetone fixation on infectivity and immunofluorescent antigenicity of respiratory syncytial virus and adenovirus type 5, lipid- and nonlipid-containing viruses, respectively. Viruses were allowed to replicate in HEp-2 cells, and the cells were then fixed in acetone at 5 C for periods ranging from 30 s to 7 days. Treatment for 10 min was sufficient to i...

Background: The main viral causes of acute respiratory diseases (ARDs) include influenza viruses A and B, respiratory syncytial virus (RSV), adenovirus (ADV), rhinovirus, and parainfluenza viruses (PIV). This study aimed to investigate the prevalence of respiratory RSV, ADV and rhinovirus in patients with flu-like symptoms admitted to Mazandaran province health centers in north of Iran. Metho...

BACKGROUND Upper respiratory tract infection (URTI) is a major reason for hospitalization in childhood. More than 80% of URTIs are viral. Etiological diagnosis of URTIs is important to make correct clinical decisions on treatment methods. However, data for viral spectrum of URTIs are very limited in Shanghai children. METHODS Nasopharyngeal swabs were collected from a group of 164 children ag...

The bovine and human respiratory syncytial viruses cause severe lower respiratory tract infections. Effective vaccines against the respiratory syncytial viruses have been lacking since vaccine failures in the 1960s and 1970s. In this report, we describe a bovine respiratory syncytial virus (bRSV) challenge model in which both classical bRSV respiratory infection and vaccine-enhanced immune path...

results among the 158 children evaluated in this study, 49 individuals (31.1%) had rsv infection while nine individuals (5.7%) had hmpv infection. five (55.5%) of the hmpv-infected children were male while four (44.5%) were female and 27 (55.2%) of the rsv-infected patients were females and 22 (44.8%) were males. the rsv infections were detected in mainly < one year old children and hmpv infect...