Restless legs syndrome (RLS) is a common neurological disorder characterized by an irresistible urge to move the legs, usually accompanied or caused by uncomfortable sensations in the legs. Symptoms are worse in the evening or at night than during the day and generally begin or worsen during periods of rest or inactivity. The chronic sleep disturbance often associated with RLS is likely due, at...

BACKGROUND In restless legs syndrome (RLS), the isolated involvement of other body parts in the absence of leg involvement is rare. CASE REPORT We report an 82-year-old male with a 1-year history of Parkinson's disease (PD) who developed an abnormal sensation limited to his "lower back." He fulfilled the four essential RLS criteria, with the major caveat that the criteria were applied in a mo...

conclusions the most important factor in diagnosis is physician’s attention and clinical experience with this condition and using irlssg. results two major theories are developed regarding the pathophysiology of rls. the first one concerns central nervous system dopamine imbalance and the second one concerns intracellular iron dysregulation. the most common used pharmacologic agents in treatmen...

Background: In restless legs syndrome (RLS), the isolated involvement of other body parts in the absence of leg involvement is rare. Case report: We report an 82-year-old male with a 1-year history of Parkinson’s disease (PD) who developed an abnormal sensation limited to his ‘‘lower back.’’ He fulfilled the four essential RLS criteria, with the major caveat that the criteria were applied in a ...

Background: Evidence is still lacking regarding the association of restless leg syndrome (RLS) on glycemic control and psychological status in diabetic patients.
 Aims: To summarize evidence RLS with adults type 2 diabetes.
 Methods: The literature search compassed all English-published studies from inception till 21st May 2023 electronic databases MEDLINE/PubMed, Cochrane Library, We...

BACKGROUND In the past few decades, much has been learned about the pathophysiology of restless legs syndrome (RLS). Investigators have studied neuropathology, imaging, electrophysiology, and genetics of RLS, identifying brain regions and biological systems affected in RLS. This manuscript will review RLS pathophysiology literature, examining the RLS state through consideration of the neuroanat...

Objective: Several groups of medications, such as dopamine blockers, analgesics and antihistaminergics were associated with restless legs syndrome (RLS). Although case reports showed some significant relations, they have many methodological limitations such as co-medications or medical co-morbidities. The aim of this study was to investigate the prevalence and severity of RLS in patients on ant...

BACKGROUND/AIM Restless legs syndrome (RLS) is a sensorymotor disorder and the core feature of this syndrome is a distressing, irresistible need or urge to move the legs. RLS is one of the most troublesome conditions experienced by endstage renal disease patients treated with regular hemodialysis, and is significantly associated with their increased mortality. The aim of this study was to asses...