Between 1976 and 1985, 110 patients had restorative proctocolectomy or proctectomy for ulcerative colitis and 103 were foilowed up until death or February 1992. There was one postoperative and one late death related to surgery. The cumulative probability of pouch failure was 12% at five years: half of the failures occurred within one year. The commonest reasons were perianal/pelvic sepsis and p...

Restorative proctocolectomy with pelvic ileal reservoir is a weli accepted option for the surgical treatment of ulcerative colitis. Acute pouchitis is a common complication and resembles acute ulcerative colitis. Patients with ulcerative colitis carry Escherichia coli that adhere to epithelial cells and thus this study examined whether acute pouchitis is associated with the carriage of adhesive...

Familial adenomatous polyposis (FAP) is an inherited disease characterized by the development of hundreds of colorectal adenomas, leading to a 100% lifetime risk of colorectal cancer. A prophylactic colectomy is recommended for patients with FAP to prevent colorectal cancer. Four surgical strategies are available for patients with FAP: proctocolectomy with permanent ileostomy, colectomy with il...

14. Bahia 55, McMahon RE, Hobbisa J et al. Pelvic ileo-anal reservoirs: A lectin histochemical study Hiatochemical J 1993; 25: 392-400. 15. Campbell AP, Merreft MN, Kettlewell M et al. Expression ofcolonic antigens by goblet and columnar epithelial cells in ileal pouch mucosa: Their association with inflammatory changes and faecal stasis. J Olin Pathol 1994; 47: 834-838. 16. Warren BE, Shepherd...

Restorative proctocolectomy is recognized as the standard procedure for colitic cancer in patients with ulcerative colitis (UC). However, whether this represents the optimal procedure for UC patients with sporadic cancer remains questionable, as functional quality of life differs substantially between patients with proctocolectomy and partial resection. This study considered possible problems a...

OBJECTIVE To evaluate postoperative adverse events and functional outcomes of patients undergoing restorative proctocolectomy with or without proximal diversion. DATA SOURCES The literature was searched by means of MEDLINE, Embase, Ovid, and Cochrane databases for all studies published from 1978 through July 15, 2005. STUDY SELECTION Comparative (randomized and nonrandomized) studies evalua...

INTRODUCTION Early postoperative complications graded according to the Clavien-Dindo classification system have not previously been correlated with long-term quality of life outcomes in patients who have had restorative proctocolectomy with ileal pouch-anal anastomosis. This study aimed to assess the severity of early postoperative complications and compared these in terms of the long-term qual...