PURPOSE Retinal detachment (RD) is associated with acute visual loss caused by anatomic displacement of the photoreceptors and with chronic visual loss/disturbance caused by retinal remodeling and photoreceptor cell death, which may occur even after successful reattachment. The P2Y(2) receptor agonist INS37217 improves the rate of retinal reattachment in animal models of induced RD, and has bee...

INTRODUCTION Choroidal coloboma is a congenital defect caused by an inadequate closure of embryonic fissure. About 40% of the eyes with the choroidal coloboma (CHC) develop the retinal detachment (RD). It is extremely difficult to manage these cases due to the lack of pigmentation at the site of choroidal coloboma. OUTLINE OF CASES This is a case series of five patients with CHC and RD who we...

OBJECTIVES To estimate the long-term cumulative incidence of and risk factors for retinal detachment (RD) after phacoemulsification using linked administrative medical data. METHODS We used the Western Australian Data Linkage System to identify patients who underwent phacoemulsification in Western Australia between January 1989 and December 2001. Retinal detachment cases were those patients r...

purpose: to compare the success rate of adjunctive 5-fluorouracil (5-fu) and low molecular weight heparin (lmwh), and daunomycin in combination with triamcinolone during vitrectomy in eyes with retinal detachment (rd) and proliferative vitreoretinopathy (pvr). methods: in this prospective randomized clinical trial, 69 eyes from 69 patients with rd and pvr (grade b or c) randomized to 3 groups. ...

the purpose of this study was to compare the anatomic and visual outcome of primary vitrectomy with scleral buckling in patients with retinal detachment following cataract surgery. fifty-six consecutive patients with retinal detachment after cataract surgery were randomly assigned to two treatment groups: standard scleral buckling and standard three-port deep vitrectomy. successful treatment wa...

PURPOSE To assess anatomic outcomes following repair of traumatic retinal detachment (RD) among a cohort of cognitively impaired adolescents with self-injurious behaviors. METHODS Main outcome measures in this retrospective, consecutive, interventional case series were retinal attachment and postoperative complications. RESULTS Complete retinal reattachment was initially achieved in all 9 e...

The inward permeability of the blood-retinal barrier to carboxyfluorescein was determined in monkey eyes with and without rhegmatogenous retinal detachment (RD). In the absence of changes in the diffusional permeability of the retinal pigment epithelium (RPE), inward permeability changes reflect changes in fluid flow across the RPE. Intravenous injection of mannitol resulted in a 15 mosmol/kg i...

Purpose Induction of focal retinal detachment (RD) for subretinal delivery of stem cells and gene therapy is increasingly common. In order to determine if this procedure has an adverse impact on the retina, we use spectral-domain optical coherence tomography (SD-OCT) to evaluate the pre- and postoperative retinal anatomy of the incidentally detached normal retina surrounding large submacular he...

PURPOSE To report the results obtained in a non-comparative series of pseudophakic patients with retinal detachment (RD) treated with vitrectomy with no associated scleral procedures. METHODS The clinical records of all pseudophakic patients with RD treated with vitrectomy were evaluated by one of the authors. Patients with primary regmatogenous RD with no signs of proliferative vitreoretinop...

BACKGROUND The purpose of the current study is to evaluate the surgical outcome for rhegmatogenous retinal detachment (RD) associated with Behçet's disease (BD). METHODS The current retrospective study included all patients operated for rhegmatogenous RD associated with BD in our institution from June 2007 to June 2012. Surgical repair was done either by scleral buckling (SB) or pars plana vi...