BACKGROUND We have previously shown that hydrogen (H2) inhalation, begun at the start of hyperoxic cardiopulmonary resuscitation, significantly improves brain and cardiac function in a rat model of cardiac arrest. Here, we examine the effectiveness of this therapeutic approach when H2 inhalation is begun on the return of spontaneous circulation (ROSC) under normoxic conditions, either alone or ...

BACKGROUND The effect of mild hypothermia (MH) on microcirculation after resuscitation from cardiac arrest is controversial. The aim of this study was to determine whether MH improves or aggravates the disturbance of cerebral microcirculation. METHODS Twenty domestic male pigs were randomized into the MH group (n = 8), non-hypothermia (NH) group (n = 8) or sham operation group (n = 4). In the...

BACKGROUND The effect of vasoconstrictors in prolonged cardiopulmonary resuscitation (CPR) has not been fully clarified. OBJECTIVES To evaluate adrenaline and vasopressin pressure effect, and observe the return of spontaneous circulation (ROSC). METHODS A prospective, randomized, blinded, and placebo-controlled study. After seven minutes of untreated ventricular fibrillation, pigs received ...

The novel coronavirus disease 2019 (COVID-19) outbreak affected the epidemiology and outcomes of Out-Of Hospital Cardiac Arrest (OHCA). We performed a retrospective observational study in Western district Vicenza (Veneto, Italy) to evaluate patients by non-traumatic OHCA we analyzed epidemiological clinical characteristics associated with sustained Return Of Spontaneous Circulation (ROSC). coll...

The implementation of the RECOVER guidelines at Small Animal Department, Faculty Veterinary Medicine Ghent University was assessed by performing both a cross-sectional research and study on impact training. During six-month prospective study, 39 patients, which underwent cardiopulmonary resuscitation (CPR), were recorded. This corresponds with an incidence 1.8% all hospitalized patients that CP...

BACKGROUND Cardiopulmonary resuscitation (CPR) after cardiac arrest is utilized indiscriminately among unselected populations. Cancer patients have particularly low rates of return of spontaneous circulation (ROSC) and survival to hospital discharge after CPR. Our study determines rates of ROSC and survival to hospital discharge among cancer patients undergoing CPR in our cancer center. We exam...

Postprandial hypotension (PPH) has not been described as a cause of hypotension after the return of spontaneous circulation (ROSC) in the intensive care unit (ICU). A 74 year old man underwent cardiopulmonary resuscitation (CPR) due to monomorphic ventricular tachycardia. After the ROSC, inotropic agents were not reduced but increased. PPH had occurred, according to the flow sheet, so a provoca...

This study aimed to explore effect of increased two-phase wave energy defibrillation on success rate of defibrillation and cardiac trauma based on current recommend energy using ventricular fibrillation pig model built by electrical stimulation in right ventricle. Twenty-four pigs were randomly divided recommend energy group (200 J), high-energy group (300 J) and ultra-high energy group (360 J)...

Abstract Aim Predicting the return of spontaneous circulation (ROSC) during cardiopulmonary resuscitation in victims cardiac arrest (CA) remains challenging. Cerebral regional oxygen saturation (rSO2) measured is feasible, and higher initial overall values seem associated with ROSC. However, these observations were limited to analysis few small single-centre studies. There a growing number stud...

AimThis observational cohort study aimed to identify factors associated with pulseless electrical activity (PEA) and asystole in in-hospital cardiac arrest (IHCA) patients determine whether differences outcome based on the initial rhythm were explained by patient- characteristics.MethodsAdults IHCA from 2017 2018 included Danish Registry (DANARREST). Additional data came population-based regist...