UNLABELLED Rhabdomyosarcoma is the most common soft tissue sarcoma in children. Metastatic rhabdomyosarcoma in children has a 5-year event-free survival rate of <30%, and a recent clinical trial with irinotecan, a topoisomerase I inhibitor, failed to improve outcome. Therefore, it was surmised that failure of irinotecan may be the result of overexpression of the DNA repair enzyme tyrosyl-DNA ph...

Rhabdomyosarcoma is a malignant neoplasm of primitive mesenchyme exhibiting skeletal muscle differentiation. Rhabdomyosarcoma, which can histopathologically be of embryonal, alveolar, botryoid and pleomorphic types; is a rare tumor in children, with an annual incidence of 4.3 cases per million. Pleomorphic rhabdomyosarcomas is a rare variant, occurring more commonly in adults. We report a rare ...

BACKGROUND Embryonal rhabdomyosarcoma of the prostate in an adult is a very rare event with only a few cases published. Diagnosis usually occurs with advanced disease frequently already with metastatic spread. In adults prognosis is very poor, therefore early diagnosis is crucial. To date, only three cases of spindle cell subtype of embryonal rhabdomyosarcoma of the prostate in an adult have be...

Rhabdomyosarcoma is the most common soft tissue sarcoma in infants and children. The peak incidence of rhabdomyosarcoma occurs in children between 2 and 5 years of age, and a second peak is seen in teenagers between 15 and 19 years of age. In the final report of 686 patients from the First Intergroup Rhabdomyosarcoma Study (IRS), the median age at diagnosis for a child presenting with rhabdomyo...

Rhabdomyosarcoma is the most common tumour of the lower genitourinary tract in children in the first two decades. Paratesticular rhabdomyosarcoma is associated with a significantly better outcome than lesions elsewhere in the genitourinary tract. Although ultrasound is considered the imaging modality of choice for evaluating intrascrotal pathology, the ultrasound appearance of paratesticular rh...

dren and they are far less frequent in adults. Histologically, they are classified into three subtypes: embryonal, alveolar and pleomorphic. While the head and neck are the principal locations for childhood rhabdomyosarcoma, head and neck rhabdomyosarcoma is rare in adults (1). The overall survival is worse for adults than for children (2). The major sites of metastases are lung, bone, bone mar...

Rhabdomyosarcoma is a common malignant soft tissue that frequently involves bone and major neurovascular structures and resection of deep-seated rhabdomyosarcoma can cause severe dysfunction in the affected limbs. Based on the mouse osteosarcoma model, we developed a new surgical approach involving photodynamic surgery (PDS), photodynamic therapy (PDT) and radiodynamic therapy (RDT) using acrid...

primary sarcoma of the breast is very rare and constitutes less than 1% of all breast cancers. herein, we report a case of pleomorphic rhabdomyosarcoma (prms) of the right breast in a 49-year-old female patient presented with a mass (7 cm × 6.5 cm). mammography and ultrasonography suspected a malignant lesion and a diagnosis of poorly differentiated carcinoma was made on fine needle aspiration ...

primary rhabdomyosarcoma (rms) of the kidney is a rare malignant mesenchymal tumor with an aggressive clinical course. adult renal rms is typically a pleomorphic histologic subtype and only a few cases have ever been reported. we herein present a new case of renal rms of the embryonal histologic subtype in a 26-year-old woman.

Introduction: Rhabdomyosarcoma is the commonest soft tissue sarcoma of childhood. The tumour commonly occurs in the body regions of the head and neck, genitourinary and extremities. Primary rhabdomyosarcoma of the breast is extremely rare and present diagnostic challenges especially in resource limited centers. It is an aggressive tumour with a poor prognosis especially when diagnosed late. Cas...