BACKGROUND Over 70-95% patients with PR3 ANCA pulmonary vasculitis present with upper respiratory tract symptoms or sings. Nasal cavity usually presents with obstruction and chronic refractory infections (rhinosinusitis) which commonly manifest as bloody discharge or crusting obstruction. Mucopurulent discharge may occur in the acute phase or remission, along with other symptoms suggesting sinu...

Over the past few years, we have witnessed numerous and continuing advances in our understanding of molecular mechanisms facilitating chronic rhinosinusitis (CRS). The current issue of the American Journal of Rhinology and Allergy contributes further to this area of study. Drilling et al.1 characterizes the in vitro activity of a bacteriophage cocktail against Staphylococcus aureus biofilms, re...

Twenty-eight patients with a clinical diagnosis of sinonasal Wegener’s granulomatosis were referred for imaging during the period 1990–2001. Of these, 10 had clinical symptoms and signs conŽned to the nose and sinuses and 18 had classical systemic Wegener’s. The computed tomography (CT) and magnetic resonance (MRI) scans of the series were reviewed by a panel of one otolaryngologist and two rad...

BACKGROUND Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic autoimmune disease that manifests as asthma, recurrent sinusitis and peripheral eosinophilia. In this study, we investigated the clinical features of the ear and nasal manifestations of EGPA in comparison with those of granulomatosis with polyangiitis (GPA). MATERIALS AND METHODS Twenty-one patients diagnosed with E...

OBJECTIVES/HYPOTHESIS To study differential diagnosis and efficacy of management strategies in patients presenting to an otolaryngologist for sinus pressure, pain, or headache. STUDY DESIGN Retrospective analysis at an academic medical center. METHODS Patients were seen in the clinic (2010-2012) for sinus-related headache, pressure, pain or fullness (study symptoms) by a rhinologist. A retr...