The internal thoracic vein is a conduit that has not been thoroughly investigated in literature as long term patency and outcomes are unknown. We present a case where the right internal thoracic vein (RITV) was used to extend a short right internal thoracic artery (RITA). The elongated composite conduit was then anastomosed to the right coronary artery (RCA). A 61-year-old male patient was refe...

Tengo el placer, como editor en jefe de las IEEE Transactions on Education de dar la bienvenida a IEEE-RITA a la familia de publicaciones de la Sociedad de la Educación del IEEE. En los dos últimos años, la Sociedad de la Educación del IEEE (IEEE-ES) ha estado explorando nuevas vías para proporcionar beneficios adicionales a sus miembros a través de sus publicaciones. Además de las IEEE Transac...

We successfully treated chronic type A dissection and coronary artery disease with a functional midline crossing right internal thoracic artery (RITA) after coronary artery bypass grafting (CABG). A 68-year-old man was incidentally diagnosed as chronic type A dissection by follow-up cardiac catheterization after CABG, with 90% stenosis in the right coronary artery (RCA) No. 2. The dissecting an...

We have previously identified the p53-reactivating compound RITA in a cell-based screen. Here, using microarray analysis, we show that the global transcriptional response of tumor cells to RITA is p53 dependent. Pathway analysis revealed induction of the p53 apoptosis pathway, consistent with apoptosis being the major response to RITA in cancer cells. We uncovered that MDM2 released from p53 by...

The Western Hemisphere genus Pseudomorpha Kirby 1825 was last revised by Notman in 1925 based on only a few known species (22) and paltry few specimens (73); other authors have added an additional six species represented by 53 additional specimens since 1925. Baehr (1997) assigned three species from Australia to this genus, albeit in a new subgenus, Austropseudomorpha Baehr 1997. A recent study...

This article evaluates the effectiveness of the RITA computer-assisted intervention for secondary school education. The RITA system is a computer-based literacy support system that assists, rather than replaces, the teacher in providing support tailored to each child's profile of reading attainments. The study consists of 8 students who were initially very seriously disadvantaged in terms of li...

Background: Cervical cancer is the third most common cancer in women throughout the world. The human papillomavirus (HPV) E6 viral protein plays an essential role in proteasomal degradation of the cancer suppressant protein p53. As a result, p53 negative regulation and apoptosis relevant activities are abrogated, facilitating development of cervical cancer. Methods: A mathematical model of E6-p...

Ewing sarcoma is one of themost frequent bone cancers in adolescence. Althoughmultidisciplinary therapy has improved the survival rate for localized tumors, a critical step is the development of new drugs to improve the long-term outcome of recurrent and metastatic disease and to reduce side effects of conventional therapy. Here, we show that the small molecule reactivation of p53 and induction...