247 Rousseaux S, Chevret E, Monteil M, Cozzi J, Pelletier R, Delafontaine D, Sele B: Sperm nuclei analysis of a Robertsonian t(14q21q) carrier, by FISH, using three plasmids and two YAC probes. Hum Genet 96: 655–660 (1995). Rubes J, Vozdova M, Kubickova S: Aneuploidy in pig sperm: multicolor fl uorescence in situ hybridization using probes for chromosomes 1, 10, and Y. Cytogenet Cell Genet 85: ...

A – Transmissible paternal/maternal genetic alterations:  Diseases that affect a single gene or monogenic (dominant, recessive or X-linked), whose mutation is known and can be analysed.  X chromosome-linked disorders, whose gene is not known or has some heterogeneity, but is avoided with sex selection.  Structural chromosomal abnormalities such as Robertsonian or reciprocal translocations. B...

Background Cytogenetic study of reproductive wastage is an important aspect in determining the genetic background of early embryogenesis. Approximately 15 to 20% of all pregnancies in humans are terminated as recurrent spontaneous abortions (RSAs). The aim of this study was to detect chromosome abnormalities in couples with RSAs and to compare our results with those reported previously. Materia...

AIM The purpose of the present research was a presentation of case report of Robertsonian translocation composed of homologous chromosomes 21q;21q and reproductive risk found in the family affected by this type oftranslocation. METHODS Cytogenetic diagnosis has been done on chromosome preparations of lymphocytes cultured from peripheral blood by Moorhead method. RESULTS Analyses of cytogene...

Populations of wild boar (Sus scrofa scrofa L.) of Central Europe frequently demonstrate polymorphism in chromosome number. This phenomenon is caused by chromosome rearrangements of the centric fusion type. The presence of Robertsonian translocations in the wild boar population may lead to one of three different karyotypes: 2n=36, 2n=37 and 2n=38. The aim of the study was to analyse the karyoty...

The telomere and centromere are two specialized structures of eukaryotic chromosomes that are essential for chromosome stability and segregation. These structures are usually characterized by large tracts of tandemly repeated DNA. In mouse, the two structures are often located in close proximity to form telocentric chromosomes. To date, no detailed sequence information is available across the m...

Aim. Fertility disorders are one of the most common problems reproductive medicine. Chromosomal abnormalities play a crucial role in failure. The main purpose our study was to determine types and frequency chromosomal aberrations couples with history infertility. Methods. Karyotyping performed 652 failure between 2004 2022, including 203 primary infertility (PI), 240 recurrent pregnancy loss (R...