This work presents results of flow simulations performed with the commercial code CFX 11.0 in a PWR 5x5 rod bundle segment with a split vane spacer grid. The geometrical configuration and flow conditions used in the experimental studies performed by Karoutas were assumed in the simulations. To make the simulation possible with a limited computational capacity and acceptable mesh refinement, the...

In cell-extracellular matrix junctions (focal adhesions), the cytoskeletal protein talin is central to the connection of integrins to the actin cytoskeleton. Talin is thought to mediate this connection via its two integrin, (at least) three actin, and several vinculin binding sites. The binding sites are cryptic in the head-to-rod autoinhibited cytoplasmic form of the protein and require (stepw...

The cytoskeletal protein talin plays a key role in activating integrins and in coupling them to the actin cytoskeleton. Its N-terminal globular head, which binds beta integrins, is linked to an extended rod having a C-terminal actin binding site and several vinculin binding sites (VBSs). The NMR structure of residues 755-889 of the rod (containing a VBS) is shown to be an amphipathic four-helix...

Abstract Thermal-hydraulic behaviors within a PWR fuel assembly is very complex under accident conditions and marine conditions, which has significant impact on reactor safety. It crucial to carry out studies thermal-hydraulic properties transient conditions. A telecentric lens pulse signal generator are applied improve the performance of PIV system, high temporal spatial resolution measurement...

The High-Resolution Gamma Tomography System (HRGTS) facility is under development at the University of Michigan. This system planned generally for application to two-phase flow loops representing nuclear fuel bundles. These measurements should provide insight into fluid dynamics phenomena and high resolution data validation computational (CFD) codes. HRGTS be deployed in Michigan Advanced Rod B...

The self-assembly structures of dumbbell-shaped supramolecules are investigated using a simple sphere-rod-sphere (SRS) model. Through the simulated annealing Monte Carlo simulation under NVT condition, two variations this model, i.e. rigid/semi-rigid compared by their order parameters. We found that, varying interactions SRS various nanostructures such as cross-linked networks, clusters phases,...