BACKGROUND Accidental poisoning with anticoagulant rodenticides is not uncommon in dogs, but few reports of the elimination kinetics and half-lives in this species have been published. Our objectives were to develop and validate a new method for the quantification of anticoagulant rodenticides in canine blood and faeces using reversed phase ultra-high performance liquid chromatography-tandem ma...

A 2.0% zinc phosphide pellet and a 0.001% brodifacoum bait gave the lowest percentage post-treatment activity in a field test in which broadcast applications were followed shortly by rain. There was not a clear difference in performance between the single-feeding toxicants and the multiple-feeding anticoagulants in this experiment. A 0.075% cholecalciferol bait gave control comparable to some r...

Cholecalciferol is an acute (single-feeding) and/or chronic (multiple-feeding) rodenticide toxicant with unique activity for controlling commensal rodents including anticoagulant-resistant rats. Cholecalciferol differs from conventional acute rodenticides in that no bait shyness is associated with consumption and time to death is delayed, with first dead rodents appearing 3-4 days after treatment.

Zinc phosphide (Zn3P2/ZnP) is used as a rodenticide. The most common signs of toxicity are nausea, vomiting, hypotension, and metabolic acidosis; patients presenting such signs are referred to the emergency department (ED) of the hospitals. Therefore, this study aimed to report two cases of hepatotoxicity following accidental and intentional ZnP poisoning and successful management with N-acetyl...

Takotsubo cardiomyopathy or left ventricular apical ballooning syndrome is an acute cardiac syndrome precipitated by emotional stress. Patients present with chest pain, ecg changes and elevated cardiac enzymes consistent with acute myocardial infarction but have normal coronary arteries on coronary angiography. Here, we report a 29 year female patient who developed the disease after ingestion o...