نتایج جستجو برای: rora
تعداد نتایج: 204 فیلتر نتایج به سال:
چکیده برآورد میزان جریان پایه و تخمین تغذیه آب زیر زمینی در یک حوضه آبخیز یکی از مهمترین مباحث مدیریت منابع آب و هیدرولوژی میباشد. از آنجایی که سیستم آبخوان - رودخانه دو جزء لاینفک محسوب میشود بنابراین بررسی ارتباط متقابل جریان پایه رودخانه با تراز سطح ایستابی آبخوان برای ارزیابی روشهای برآورد تغذیه آب زیرزمینی امری ضروری است. در این مطالعه از نرم افزارهای PART و RORA برای تفکیک جریان پایه ...
Streptomyces linear plasmids and linear chromosomes can replicate also in a circular form when their telomeres are deleted. The 17-kb linear plasmid pSLA2 has been a useful model in studies of such replicons. Here we report that the minimal origin initiating replication of pSLA2-derived plasmids as circular molecules cannot propagate these plasmids in a linear mode unless they also contain a no...
The homozygous mutant mouse staggerer (RORa(sg)/RORa(sg)), was initially described as ataxic, due to the presence of massive neurodegeneration in the cerebellum [Science 136 (1962) 610]. The identification of the widely expressed Retinoic acid receptor-related Orphan Receptor, NR1F1 (RORalpha) gene as the site of mutation in the staggerer mouse has led to great progress in understanding the mol...
Night shift work has been associated with an increased risk of breast cancer pointing to a role of circadian disruption. We investigated the role of circadian clock gene polymorphisms and their interaction with nightwork in breast cancer risk in a population-based case-control study in France including 1126 breast cancer cases and 1174 controls. We estimated breast cancer risk associated with e...
As the Internet has evolved and grown, an increasing number of nodes (hosts or autonomous systems) have become multihomed, i.e., a node is connected to more than one network. Mobility can be viewed as a special case of multihoming—as a node moves, it unsubscribes from one network and subscribes to another, which is akin to one interface becoming inactive and another active. The current Internet...
BACKGROUND Dysfunction of the circadian clock and single polymorphisms of some circadian genes have been linked to cancer susceptibility, although data are scarce and findings inconsistent. We aimed to investigate the association between circadian pathway genetic variation and risk of developing common cancers based on the findings of genome-wide association studies (GWASs). METHODS Single nu...
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