Rubbing a topical formulation on skin is generally assumed to enhance drug penetration. The aim of this study was to demonstrate different techniques such as using glass rod, rheometer, and gloved finger for rubbing a 2% salicylic acid gel on skin and investigate their effect on in vitro permeation of salicylic acid through dermatomed porcine ear skin. The studies included evaluation of the gel...

In this article, we propose a mechanical rubbing method to eliminate the optical bounce and decrease the response time of homeotropic liquid crystal (LC) cells with sputtered silicon dioxide alignment films. After gently rubbing the inorganic alignment film (sputtered silicon oxide, SiO2), the decreasing polar anchoring energy results in slightly smaller pretilt angle which gives LC a toppling ...

We report a significant role of side chains in the propagation of molecular orientation upon annealing the liquid crystal phase of polyfluorenes. Direct rubbing of poly(9,9-di(octyl)fluorene) led to the orientation of polymer segments in the top-most region of the film and enhanced propagation of this orientation along the rubbing direction was observed upon annealing. In contrast, the rubbing-...

PURPOSE To present a case of autosomal dominant dystrophic epidermolysis bullosa with symblepharon formation due to eye rubbing. CASE REPORT A 10-year-old girl suffering from blistering and ulcerative lesions of the trunk and palms and dystrophic nails since childhood was referred to our clinic with a symblepharon connecting the medial portion of the right upper lid to the superonasal quadran...

The possible role of endothelium in the vascular responses to vasodilator drugs was studied in relation to experimental hypertension. Short ring segments of the thoracic aorta and femoral artery were removed from spontaneously hypertensive rats (SHR) and normotensive WistarKyoto (WKY) rats. They were rubbed on the intimal surface to destruct endothelial cells or unrubbed, and bathed in Krebs-bi...

An integrated model for keratectasia risk assessment has received much attention over many years. The objective of this article is to propose a more complete, conceptual model by which high risk individuals can be screened, even with no topographic irregularity or corneal thinning. In this model, corneal ectasia results from the fatigue effect of cyclic shear stress and tensile stress, caused b...

CONTEXT Surgical site infections prolong hospital stays, are among the leading nosocomial causes of morbidity, and a source of excess medical costs. Clinical studies comparing the risk of nosocomial infection after different hand antisepsis protocols are scarce. OBJECTIVE To compare the effectiveness of hand-cleansing protocols in preventing surgical site infections during routine surgical pr...

Abstract High temperature rubbing is a fast and low‐cost method that can align semi‐crystalline polymers such as poly(lactic acid) (PLA) by application of shear‐force via rotating cylinder covered with microfiber cloth on thin film maintained at high temperature. A multi technique approach uncovers the role thickness PLA structure. Both poly( l ‐lactic (PLLA) stereo‐complex (SC‐PLA) be readily ...

OBJECTIVES This study investigated whether increasing the concentration of acidic monomers in one-step adhesives would allow reducing their application time without interfering with the bonding ability to primary enamel and dentin. MATERIAL AND METHODS Experimental one-step self-etch adhesives were formulated with 5 wt% (AD5), 20 wt% (AD20), or 35 wt% (AD35) acidic monomer. The adhesives were...