To the Editor: A 63-year-old man presented with a prior diagnosis of severe psoriasis affecting the extremities, neck, face, and scalp of 1 year’s duration. He reported pain, itching, and swelling in the affected areas. He felt the rash was worst on the hands and feet, and pain made performing activities of daily living difficult. His treatment regimen at presentation included triamcinolone cre...

Sir, Pityriasis rubra pilaris (PRP) is an uncommon, idiopathic, papulosquamous disorder that often progresses to erythroderma and causes disabling keratoderma. The disease is classified into 5 groups on the basis of clinical appearance, behaviour and prognosis, as proposed by Griffiths in 1980 (1). Recently, a sixth group has been proposed in order to acknowledge the HIV-associated type of PRP ...

Acute postinfectious pityriasis rubra pilaris (PRP) is a variant of juvenile PRP (Griffiths type III) characterized by no family history, an acute course associated with a prior fever, and good prognosis. Clinical features may resemble other superantigen-mediated diseases, such as scarlatiniform rash or staphylococcal scalded skin syndrome, but its histology and treatment are different. We pres...

Observation: Pityriasis rubra pilaris (PRP) is characterized by redness of the skin, and scaling with a variable degree of pruritus. It may rarely coexist with various neuromuscular diseases. There are many reports of multiple diseases such as pemphigus, vitiligo, alopecia areata, systemic lupus erythematosus, lichen planus, Sjögren’s syndrome, ulcerative colitis, Hashimoto’s thyroiditis, rheum...

Background Alitretinoin is a vitamin A derivative. It’s a pan-agonist of Retinoic Acid Receptors and Retinoid X Receptors. It interferes with keratinocytes’ proliferation and differentiation and exerts immunomodulatory and anti-inflammatory activity. Its clinical efficacy in the treatment of chronic hand eczema is well demonstrated. Recently, various case reports and case series pointed out its...