Thirty samples of Indonesian medicinal plants were analyzed for their capacity to inhibit in vitro metabolism by human cytochrome P450 3A4 (CYP3A4) and CYP2D6 with a radiometric assay. The MeOH-soluble fractions of 25 samples, prepared from water extracts, demonstrated inhibitory activity more than 50% on the metabolism mediated by CYP3A4, and 21 samples on the metabolism mediated by CYP2D6. Am...

Naïve adults and larvae of the native lady beetles Coleomegilla maculata (DeGeer), Cycloneda munda (Say), Hippodamia convergens Guérin-Méneville, Olla v-nigrum (Mulsant), and the exotic lady beetle Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae) were tested for their initial response to eggs of these five lady beetle species and for egg consumption on first contact and after 3 h. Additio...

BACKGROUND Sugarcane is one of the most important crops in Brazil, mainly because of its use in biofuel production. Recent studies have sought to determine the role of sugarcane endophytic microbial diversity in microorganism-plant interactions, and their biotechnological potential. Epicoccum nigrum is an important sugarcane endophytic fungus that has been associated with the biological control...

It has been proposed that non-protein thiols and organic acids play a major role in cadmium phytoavailability distribution plants. In the Cd-hyperaccumulator Solanum nigrum non-accumulator melongena, of these ligands accumulation detoxification mechanisms Cd are debated. this study, we used X-ray absorption spectroscopy to investigate speciation plants (roots, stem, leaves) soils for their cult...

In the present study aqueous extract of Piper nigrum seeds and Vinca rosea flowers were administered orally to alloxan induced diabetic rats once a day for 4 weeks. These treatments lead to significant lowering of blood sugar level and reduction in serum lipids. The levels of antioxidant enzymes, catalase and glutathione peroxidase decreased in alloxan induced diabetic rats however these levels...

Using geometric morphometric (GM) techniques, we quantified intra and interspecific variation in female body shape using five collections each of Etheostoma caeruleum Storer, Etheostoma nigrum Rafinesque, and Etheostoma stigmaeum (Jordan). Nested multivariate analysis of variance showed significant variation in body shape among populations (Wilks’ L1⁄4 0.0687, F144,7585.11⁄4 19.35, P< 0.0001), ...

Solanum nigrum Linn. is extensively used in Indian traditional and folk medicines to cure various skin ailments. The present study aims to evaluate the possibility for the presence of novel bio-active compounds against fungal pathogens. To determine antifungal activity, aqueous and crude extracts from leaves of S. nigrum Linn. was used against A. niger, A. flavus, C. albicans by dry weight meth...

BACKGROUND Solanum nigrum is claimed in traditional medical practice, to be useful in the treatment of epilepsy in some parts of Nigeria. OBJECTIVES To study the anti-convulsant property of the aqueous extract of the leaves of S. nigrum in chicks, mice and rats. METHOD Aqueous extracts were administered intraperitoneally, at a pre-treatment time of 30 minutes, at graded doses and animals we...

Methanol extracts from 27 medicinal plant species were tested at concentrations of 0.5, 1 and 2 mg/mL for their in vivo fungicidal activities against six phytopathogenic fungi. Their efficacy varied with plant pathogen, tissue sampled and plant species. Very strong fungicidal activity was produced by extracts of Boswellia carterii, Saussurea lappa, Glycyrrhiza uralensis, Piper nigrum, Rheum cor...

Solanum nigrum is used in various traditional medical systems for antiproliferative, antiinflammatory, antiseizure and hepatoprotective activities. We have evaluated organic solvent and aqueous extracts obtained from berries of Solanum nigrum for antiproliferative activity on leukemic cell lines, Jurkat and HL-60 (Human promyelocytic leukemia cells). The cell viability after the treatment with ...