Transdermal drug delivery systems of salbutamol sulphate using eudragit RL100 and PVP were developed by solvent casting technique employing mercury as a substrate. Propylene glycol was used as a plasticizer. The prepared films exhibited satisfactory physico-chemical characteristics. In vitro permeation profiles across the guinea-pig dorsal skin using K-C diffusion cell are reported. Incorporati...

Objective of the present work is to develop orodispersible tablets of Salbutamol sulphate to improve bioavailability, disintegration time, dissolution efficacy and patient compliance. Orodispersible tablets are the fast growing and highly accepted drug delivery system in now days mainly to improve patient compliance. Orodispersible tablets have number of advantages over conventional dosage form...

Aim: The objective of the present research work was to formulate and compare two different kinds of penetration enhancer in transdermal patch with placebo patch using a drug (Salbutamol sulphate) and compare for in vitro drug release. Study Design: The transdermal patches of Salbutamol sulphate were prepared by solvent evaporation technique using different ratios of Hydroxy propyl methylcellulo...

The objective of this manuscript is to find area under the plasma concentrationtime curve (AUC) for multiple doses of salbutamol sulphate sustained release tablets (Ventolin oral tablets SR 8 mg, GSK, Pakistan) in the group of 18 healthy adults by using computational mathematics techniques. Following the administration of 4 doses of Ventolin tablets 12 hourly to 24 healthy human subjects and bi...

Cough may be the presenting feature ofasthma in adults and children.12 Treatments for asthma, such as f stimulant drugs, are known to be effective in controlling the symptom.1 Ellul-Micaleff demonstrated the efficacy of oral terbutaline sulphate in a double blind, placebo controlled crossover study of 30 patients with chronic "allergic" cough.3 In whooping cough. inhaled salbutamol has been fou...

Cough may be the presenting feature ofasthma in adults and children.12 Treatments for asthma, such as f stimulant drugs, are known to be effective in controlling the symptom.1 Ellul-Micaleff demonstrated the efficacy of oral terbutaline sulphate in a double blind, placebo controlled crossover study of 30 patients with chronic "allergic" cough.3 In whooping cough. inhaled salbutamol has been fou...