Salicylic acid-deficient NahG transgenic lines and sid2 mutants were used to evaluate the role of this compound in the development of the short-lived, annual plant Arabidopsis thaliana, with a particular focus on the interplay between salicylic acid and other phytohormones. Low salicylic acid levels led to increased growth, as well as to smaller abscisic acid levels and reduced damage to PSII (...

Salicylic acid can mitigate the impacts of salinity and drought stresses in crops. To study the effect of salicylic acid under iso-osmotic drought and salt stresses on nutrients absorption and growth of linseed (Linum usitatissimum L.), an experiment was conducted based on a completely randomized design with three replications in Yasouj University in 2016. Treatments included salinity and droug...

The activation of programmed cell death (PCD) is often a result of complex signalling pathways whose relationship and intersection are not well understood. We recently described a PCD root hair assay and proposed that it could be used to rapidly screen genetic or pharmacological modulators of PCD. To further assess the applicability of the root hair assay for studying multiple signalling pathwa...

Salicylic acid, salicyluric acid, and gentisic acid in plasma are specifically quantitated (ultraviolet detection at 313 nm) with an octadecyl silane reversed-phase chromatographic column by peak-height determination or by peak-height ratios (internal standard, o-methoxybenzoic acid). Sample preparation requires addition of an equal volume of methyl cyanide (with or without the internal standar...

Oxidation of anthracyclines leads to their degradation and inactivation. This process is carried out by peroxidases in the presence of a catalytic cofactor, a good peroxidase substrate. Here, we investigated the effect of salicylic acid, a commonly used anti-inflammatory and analgesic agent, on the peroxidative metabolism of anthracyclines. We report that at pharmacologically relevant concentra...

Invasion of vascular endothelial cells by Staphylococcus aureus is associated with diverse complications and recurrent infection. Little is known about the effect of salicylic acid, the major metabolite of aspirin, on the interaction between S. aureus and vascular endothelial cells. We examined the adhesion of S. aureus strain 8325-4 cultured with or without salicylic acid to human umbilical ve...

AIM To examine sera for the presence of salicylic acid and 2,3- and 2,5-dihydroxybenzoic acids (2,3- and 2,5-DHBA), in individuals not taking salicylate drugs. METHODS Extracts of acidified serum samples were analysed by high performance liquid chromatography with electro-chemical detection. The chromatographic conditions were altered, and the retention times of the unknown compounds compared...