OBJECTIVES The main goal was to gain insights into the pharmacokinetics of intrapericardial drug delivery using magnetic resonance (MR) imaging analysis and the extracellular MR contrast agent gadopentetate dimeglumine (Gd-DTPA) as a model. BACKGROUND Recent development of catheter-based techniques to access the intact pericardial space has increased interest in intrapericardial delivery for ...

PURPOSE To investigate the utility of dynamic contrast-enhanced gradient-echo MR imaging of head and neck lesions and to compare this technique with the commonly used spin-echo contrast-enhanced fat-saturation technique. METHODS Twenty-two patients with a total of 23 head and neck neoplasms underwent dynamic gradient-echo and spin-echo MR imaging studies. The spin-echo and dynamic gradient-ec...

Abstract AIMS To monitor changes in IVIM parameters response to JAS239 treatment preclinical glioblastoma models. METHOD C57BL/6 mice were injected intracranially with 5x105 GL261 cells and tumours observed on T2 weighted MRI. Mice imaged day 0 (T0, baseline), 3 (T3), 6 (T6) of post-treatment 10 (T10). DWI was performed using a single-shot spin-echo echo planar sequence processed Matlab acquire...

Introduction: Two techniques have been presented in the last year to acquire both angiographic and venographic information in a single acquisition (MRAV) using susceptibility weighted imaging (SWI). One uses a double echo approach with the shorter echo used for the angiography and the longer echo used for the venography (1). The other uses a single echo that is a compromise between the two with...