In order to investigate the potential of a Sanguisorba officinalis root extract as an active ingredient for wrinkle-care cosmetics, we measured its free radical scavenging activity, elastase inhibitory activity, expression of MMP-1 (matrix metalloprotease-1) in vitro, and type I collagen synthesis in normal human fibroblast cells. To isolate the main components from the S. officinalis root extr...

Sanguisorba minor Scop. is a wild edible species distributed in the Mediterranean area and present numerous traditional food recipes. In study, assessment of nutritional value (ash, carbohydrates, fat, proteins, energy, free sugars, organic acids, tocopherols, fatty acid composition, minerals) domesticated S. plants was performed. Results showed an increase ash, protein, acid, α-tocopherol cont...

Sanguisorba officinalis L. is known to have anti-inflammatory properties. However, the potential effects of S. officinalis against asthma have not been reported. In the present study, we investigated the protective effects and underlying mechanisms of S. officinalis in a murine ovalbumin (OVA)-induced asthma model. Mice were sensitized and challenged by OVA inhalation to induce airway inflammat...

"NY TWO PEOPLE can travel the same road ftand see different things. Thus, others discussing the history of renal transplantation might have noted different landmarks. Valuable personal reminiscences have been written by R.Y. CaIne of England l and J.E. Murray of Boston,2 whose initially separate careers came together in a remarkable joint venture at Harvard in 1960. In addition, original articl...

The preface to the 6th edition of Human Nutrition and Dietetics (Davidson & Passmore, 1975) begins with the statement that ‘At the present time a knowledge of nutrition is of growing importance because of the increase in world population. In 1974 the World Food Conference in Rome (United Nations, 1975) and the World Population Conference in Bucharest (United Nations, 1974) reflected the concern...

Mackay and Burnet's Autoimmune diseases, published in 1962, marked the beginning of autoimmunity as a clinical science and led to the future acceptance of the existence of autoimmunity. While there is still controversy regarding the mechanisms of autoimmunity, the authors' insightful hypothesis based on clonal selection theory and the emergence of "forbidden clones", due to somatic mutations, i...