GD Over the last decade, pathology and diagnostics have assumed a new importance in sarcoma. In the past, the belief was that all sarcomas were alike: some were bone sarcomas and some were soft-tissue sarcomas, but it did not matter because the only treatment available if surgery and radiotherapy failed was chemotherapy, and this was only rarely directed at specific subtypes of sarcomas. Some s...

Well-differentiated fibrosarcomas and anaplastic sarcomas developed in the s.c. tissues of four low-leukemia strains of mice (BALB/cf/Ki, Af/Ki, C3H/KÌand C3Hf/Ki) as well as two high-leukemia strains (AKR/Ki and C58/KÌ) following a single injection of benzpyrene (0.004 mg/g body weight) as young adults. The incidence of sarcomas was significantly less in both high-leukemia strains than that ...

Well-differentiated fibrosarcomas and anaplastic sarcomas developed in the s.c. tissues of four low-leukemia strains of mice (BALB/cf/Ki, Af/Ki, C3H/KÌand C3Hf/Ki) as well as two high-leukemia strains (AKR/Ki and C58/KÌ) following a single injection of benzpyrene (0.004 mg/g body weight) as young adults. The incidence of sarcomas was significantly less in both high-leukemia strains than that ...

Despite the development and implementation of new regimens methods adjuvant therapy, one complex problems modern oncology is treatment malignant tumours pelvic bones, which reflected in low survival rates a high percentage postoperative complications. The article provides review literature on problem diagnosis, pathology, preoperative planning intraoperative navigation with definition resection...

Uterine sarcomas are rare, aggressive mesenchymal tumours with a relatively poor prognosis. The term comprises various histological subtypes, such as leiomyosarcoma, endometrial stromal sarcomas as well as undifferentiated uterine sarcomas, which require different operative and systemic/radiation therapy strategies accordingly. The evidence on operative, adjuvant and palliative treatment curren...

Sarcomas represent a heterogeneous group of cancers thought to originate from malignant transformation of mesenchymal cells. There is increasing evidence that many, if not all, sarcomas contain within them tumor-initiating, or "cancer stem," cells responsible for the initiation, maintenance, and potentially relapse and metastasis of the tumor. Various techniques have been adopted in recent year...

Cytokeratin expression has been documented in a variety of sarcomas including synovial sarcomas, epithelioid sarcomas, Ewing's sarcomas and, rarely, osteosarcomas. In osteosarcomas immunohistochemically shown to expression cytokeratins, a component of epithelioid cells is generally present. These epithelioid cytokeratin positive cells raise the possibility of metastatic disease with prognostic ...

Introduction. Adult pelvic soft tissue sarcomas are a rare group of heterogeneous malignancies. These sarcomas differ from extremity and trunk soft tissue sarcomas in presentation, characteristics and response to treatment.Methods. A retrospective analysis of patient and tumor characteristics, treatment and prognosis and prognostic factors was performed.Results. Between 1977 and 1997, a total o...