A sarcomatoid component can occur in all histologic subtypes of renal cell carcinoma (RCC) and indicates an aggressive tumor. It is reported in literature that the sarcomatoid component can resemble fibrosarcoma, malignant fibrous histiocytoma or rhabdomyosarcoma. We describe the case of a 59-years old patient diagnosed with a chromophobe renal cell carcinoma, presenting a very rare osteosarcom...

Colonic sarcomatoid carcinomas are known to be extremely rare tumors, with only 22 cases reported either as sarcomatoid carcinomas or carcinosarcomas in the literature. The known characteristics are rapid growth, a high recurrence rate, and an extremely poor prognosis. Herein we report a case of a patient who had a sarcomatoid carcinoma of the sigmoid colon and died only 22 days after surgery d...

A case of sarcomatoid malignant pleural mesothelioma showing extremely rare growth pattern is described. A 63-year-old man presented to our hospital with left pleural effusion. A computed tomography (CT) scan of the chest showed diffusely thickened left visceral and parietal pleura associated with intermingled pulmonary infiltrative shadowing. Biopsy of the pleura under general anaesthesia conf...

BACKGROUND Pulmonary metastasis from prostate cancer is considered to be a late event, and patients can be treated with chemotherapy or hormonal manipulation. However, there has been only a few reports on surgical resection for pulmonary metastasis from prostate cancer. CASE PRESENTATION We present a surgical case of solitary pulmonary metastasis from prostate cancer. A 73-year-old man underw...

Sarcomatoid carcinoma is a type of spindle cell neoplasm. These varieties neoplasms comprise diverse collection benign and malignant neoplasms. carcinoma, also known by various other names such as Spindle Lane’s tumor, to name few, an exceedingly rare aggressive variant squamous 3, 7, 8 The variation in its nomenclature reflects the divergent interpretation sarcomatoid component reactive or neo...

Cholangiocarcinoma (CC) is an adenocarcinoma arising from epithelial cells of varying locations within the biliary tree, and is the second most common primary liver tumor, accounting for approximately 10-15% of all hepatobiliary malignancies. This disease has a high prevalence in Southeast and Eastern Asia, including Korea; during the period 2003-2005, the age-standardized incidence rates of in...

Sarcomatoid combined hepatocellular-cholangiocarcinoma is an extremely rare primary hepatic malignancy and only a few cases have been reported. Herein, we report a case of combined hepatocellular-cholangiocarcinoma with sarcomatoid changes in a 52-year-old man, who had a history of liver cirrhosis and transarterial chemoembolization. The resected liver revealed a mass of 4.5×3.5 cm. Microscopic...

The author reports a very rare and very unique urinary bladder carcinoma. This carcinoma occurred in a 68-year-old Japanese patient who underwent cystectomy for bladder tumor. The tumor was large polypoid and ulcerated one. Histologically, the tumor consisted of the following three elements: giant cell sarcomatoid carcinoma (70% in area), squamous cell carcinoma (20% in area), and papillary uro...

Cutaneous spindle cell malignancies such as sarcomatoid squamous cell carcinoma (SCC), leiomyosarcoma, desmoplastic melanoma (DM) and atypical fibroxanthoma (AFX) may be morphologically indistinguishable, yet accurate diagnosis is important for appropriate clinical management. The distinction among these entities relies on immunohistochemical evaluation for epidermal, muscle or melanocytic diff...

Dedifferentiation, or decreased processing specificity, has been suggested to represent a ubiquitous characteristic of cognitive aging. In this study, we examined both age-related differences and intra-group differences in neural specificity in the ventral visual cortex for color, words, faces and places. Our results demonstrated that neural dedifferentiation was not ubiquitous across stimulus ...