The antinociceptive activity of the methanolic extract of the leaves of Feronia limonia Linn. (Family Rutaceae) was investigated using acetic acid-induced writhing model and tail flick test in swiss albino mice. The extract produced about 26.01% ( p< 0.01), 39.88% ( p< 0.01) and 57.07% (p< 0.01) writhing inhibition at the dose of 100, 200 and 400 mg/kg of body weight respectively, which was com...

The present study explores the potential of nanoemulsion, a lipid drug delivery system, to improve solubility and oral absorption of Silybum marianum extract. The optimized formulation contained 40 mg/mL of commercial extract (4 % w/w) and it was composed of 2.5 g labrasol (20 %) as the oil phase, 1.5 g cremophor EL as the surfactant, and 1 g labrafil as the cosurfactant (mixture surfactant/cos...

Diets low in saturated fat and cholesterol are recommended to the American public for improving plasma lipoprotein patterns and reducing the risk of heart disease. However, since dietary intake cannot always be controlled, the effects of different degrees of dietary saturated fat lowering and occasional high saturated fat and cholesterol meals on the expected lipoprotein pattern improvement of ...

Background: The Gundilia tournefortii leaf contains the chemical compound such as saturated and unsaturated fatty acids. Saturated fatty acid includes stearic and palmitic acid and unsaturated include linoleic and oleic acid, that, these compounds inhibit 5 reductase enzyme. The present study was carried out with the aim of determining the effect of Gundilia tournefortii leaf on spermatogenesis...

The National Bureau of Standards conventional activity scale of pH is defined by a series of standard buffer solutions prepared from certified materials issued as N BS Stan dard Samples. The five standards thus far established cover the pH range 1.68 to 9.18 at 25° . In order to increa e t he accuracy of m easurements at high pH, a highly alkaline standard is needed. A solut ion of calci um hyd...

The aim of the present study was to examine the effect of reducing saturated fat in the diet, or partly replacing it with unsaturated fat, on the serum lipoprotein profile of human subjects. The study had two intervention periods, 8 weeks (phase 1) and 52 weeks (phase 2). In phase 1, total fat was reduced from 31 to 25% energy (polyunsaturated fatty acids (PUFA):saturated fatty acids (SFA) rati...