Seventy-seven patients with recurrent radicular symptoms after operation for lumbar disk herniation were examined by plain computed tomography (CT) and by intravenously enhanced CT. With the latter technique, scar tissue and recurrent disk herniation can be distinguished: scar tissue shows definite contrast enhancement whereas recurrent disk herniation remains unenhanced. Nerve roots surrounded...

Although hypertrophic scarring commonly occurs following burns, many aspects such as incidence of and optimal treatment for scar hypertrophy remain unclear. This review will focus on hypertrophic scar formation after burn in particular, exploring multiple treatment options and describing their properties as well as effectiveness. To evaluate treatment efficacy and scar development, clinical sca...

The formation of hypertrophic scars (HSs) is a fibroproliferative disorder of abnormal wound healing. HSs usually characterize excessive proliferation of fibroblasts, abnormal deposition of extracellular matrix (ECM) during wound healing, associated with cosmetic, functional, and psychological problems. Owing to the role of ECM proteins in scar formation, we comparatively analyzed matrix protei...

The fibrotic scar formed after central nervous system injury has been considered an obstacle to axonal regeneration. The present study was designed to examine whether cell transplantation into a damaged central nervous system can reduce fibrotic scar formation and promote axonal regeneration. Nigrostriatal dopaminergic axons were unilaterally transected in rats and cultures of olfactory-ensheat...

A macroscopically visible scar was present at birth in three infants with a history of injury during amniocentesis at 16-20 weeks' gestation. In several neonates born between 21 and 31 weeks' gestation, chemical injury to the skin caused by extravasation of calcium gluconate healed by formation of a large scar. In the infant born at 21 weeks, biopsy of the injured area showed infiltration by la...

Excess scar formation secondary to traumatic or surgical injuries can have devastating consequences, ranging from body disfigurement to organ dysfunction. Hypertrophic scars and keloids are skin fibrotic conditions that can be caused by minor insults to skin, such as acne or ear piercing, or by severe injuries such as burns. Differences between keloids, hypertrophic scars and normal scars inclu...

Background and Design: The aim of this study is to investigate whether there can be a difference in types of scars developed on the same type of incisions due to cesarean section or benign gynecologic operations, and to examine the effect of regenerative process occurring in the puerperal period on scar formation. Materials and Methods: A total of 586 female patients aged 20-40 years, who appli...